PDLIM5

PDLIM5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2UZC, 2DAR
Dynodwyr
Cyfenwau	PDLIM5, ENH, ENH1, LIM, L9, PDZ and LIM domain 5
Dynodwyr allanol	OMIM: 605904 HomoloGene: 21289 GeneCards: PDLIM5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • protein N-terminus binding • actin binding • actinin binding • protein kinase C binding • cadherin binding involved in cell-cell adhesion • muscle alpha-actinin binding Cydrannau o'r gell • cytoplasm • cell junction • neuron projection • postsynaptic membrane • Cellbilen • synapse • actin cytoskeleton • bilen • GO:0097483, GO:0097481 postsynaptic density • cytosol • stress fiber • Z disc • filamentous actin Prosesau biolegol • regulation of dendritic spine morphogenesis • regulation of synapse assembly • cell-cell adhesion • cell growth involved in cardiac muscle cell development • heart development • actin cytoskeleton organization • muscle structure development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10611	n/a
Ensembl	ENSG00000163110	n/a
UniProt	Q96HC4	n/a
RefSeq (mRNA)	NM_001011513 NM_001011515 NM_001011516 NM_001256425 NM_001256426 NM_001256427 NM_001256428 NM_001256429 NM_006457	n/a
RefSeq (protein)	NP_001011513 NP_001011515 NP_001011516 NP_001243354 NP_001243355 NP_001243356 NP_001243357 NP_001243358 NP_006448	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDLIM5 yw PDLIM5 a elwir hefyd yn PDZ and LIM domain 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDLIM5.

• L9
• ENH
• LIM
• ENH1

Llyfryddiaeth

• "Peripheral PDLIM5 expression in bipolar disorder and the effect of olanzapine administration. ". BMC Med Genet. 2012. PMID 23031404.
• "LIM domains regulate protein kinase C activity: a novel molecular function. ". Cell Signal. 2011. PMID 21266195.
• "Polymorphisms in PDLIM5 gene are associated with alcohol dependence, type 2 diabetes, and hypertension. ". J Psychiatr Res. 2017. PMID 27693979.
• "Bayesian logistic regression in detection of gene-steroid interaction for cancer at PDLIM5 locus. ". J Genet. 2016. PMID 27350677.
• "Nonsynonymous polymorphisms of the PDLIM5 gene association with the occurrence of both bipolar disorder and schizophrenia.". Psychiatr Genet. 2013. PMID 24064681.