PDLIM4

PDLIM4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EEG, 2V1W, 4Q2O
Dynodwyr
Cyfenwau	PDLIM4, RIL, PDZ and LIM domain 4
Dynodwyr allanol	OMIM: 603422 HomoloGene: 2735 GeneCards: PDLIM4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • GO:0001948, GO:0016582 protein binding • protein phosphatase binding • protein homodimerization activity • alpha-actinin binding • actin binding • muscle alpha-actinin binding Cydrannau o'r gell • stress fiber • early endosome lumen • filamentous actin • recycling endosome lumen • postsynaptic membrane • cnewyllyn cell • cytoplasm • endosome • Cytosgerbwd • bilen • lamellipodium • cell junction • early endosome membrane • cell projection • neuron projection • dendritic spine • synapse • perinuclear region of cytoplasm • recycling endosome membrane • Z disc Prosesau biolegol • actin cytoskeleton reorganization • excitatory chemical synaptic transmission • heart development • actin cytoskeleton organization • muscle structure development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8572	n/a
Ensembl	ENSG00000131435	n/a
UniProt	P50479	n/a
RefSeq (mRNA)	NM_003687 NM_001131027	n/a
RefSeq (protein)	NP_001124499 NP_003678	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDLIM4 yw PDLIM4 a elwir hefyd yn PDZ and LIM domain 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDLIM4.

• RIL

Llyfryddiaeth

• "A structural portrait of the PDZ domain family. ". J Mol Biol. 2014. PMID 25158098.
• "PDLIM4, an actin binding protein, suppresses prostate cancer cell growth. ". Cancer Invest. 2009. PMID 19212833.
• "RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis. ". Cancer Res. 2007. PMID 17332327.
• "Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women. ". J Hum Genet. 2003. PMID 12908099.
• "The human RIL gene: mapping to human chromosome 5q31.1, genomic organization and alternative transcripts.". Gene. 1998. PMID 9573374.