PDE6G

PDE6G
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3JWR
Dynodwyr
Cyfenwau	PDE6G, PDEG, RP57, phosphodiesterase 6G
Dynodwyr allanol	OMIM: 180073 HomoloGene: 1955 GeneCards: PDE6G
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0048551 enzyme inhibitor activity • spectrin binding • cGMP binding • GO:0001948, GO:0016582 protein binding • 3',5'-cyclic-GMP phosphodiesterase activity • 3',5'-cyclic-nucleotide phosphodiesterase activity • hydrolase activity Cydrannau o'r gell • Cellbilen • photoreceptor disc membrane • photoreceptor outer segment membrane Prosesau biolegol • positive regulation of G protein-coupled receptor signaling pathway • positive regulation of epidermal growth factor receptor signaling pathway • golwg • response to stimulus • regulation of rhodopsin mediated signaling pathway • GO:0048553 negative regulation of catalytic activity • Wnt signaling pathway, calcium modulating pathway • rhodopsin mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5148	n/a
Ensembl	ENSG00000185527	n/a
UniProt	P18545	n/a
RefSeq (mRNA)	NM_002602 NM_001365724 NM_001365725	n/a
RefSeq (protein)	NP_002593 NP_001352653 NP_001352654	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDE6G yw PDE6G a elwir hefyd yn Phosphodiesterase 6G (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 17, band 17q25.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDE6G.

• PDEG
• RP57

Llyfryddiaeth

• "Physical and genetic localization of the gamma subunit of the cyclic GMP phosphodiesterase on the long arm of chromosome 17 (17q25). ". Genomics. 1993. PMID 8406511.
• "Evaluation of the gene encoding the gamma subunit of rod phosphodiesterase in retinitis pigmentosa. ". Invest Ophthalmol Vis Sci. 1994. PMID 8125719.
• "Phosphodiesterase 6 subunits are expressed and altered in idiopathic pulmonary fibrosis. ". Respir Res. 2010. PMID 20979602.
• "Autosomal-recessive early-onset retinitis pigmentosa caused by a mutation in PDE6G, the gene encoding the gamma subunit of rod cGMP phosphodiesterase. ". Am J Hum Genet. 2010. PMID 20655036.
• "Determinants for phosphodiesterase 6 inhibition by its gamma-subunit.". Biochemistry. 2010. PMID 20397626.