PDE6D

PDE6D
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1KSG, 1KSH, 1KSJ, 3T5G, 3T5I, 4JHP, 4JV6, 4JV8, 4JVB, 4JVF, 5E8F, 5E80, 5F2U
Dynodwyr
Cyfenwau	PDE6D, JBTS22, PDED, phosphodiesterase 6D
Dynodwyr allanol	OMIM: 602676 HomoloGene: 1954 GeneCards: PDE6D
EC number	3.1.4.35
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GTPase inhibitor activity • GO:0001948, GO:0016582 protein binding • 3',5'-cyclic-nucleotide phosphodiesterase activity Cydrannau o'r gell • cytoplasm • cytosol • cell projection • Cytosgerbwd • cytoplasmic vesicle membrane • bilen • GO:0016023 cytoplasmic vesicle • cilium Prosesau biolegol • GO:0034259 negative regulation of GTPase activity • response to stimulus • golwg • sensory perception of light stimulus Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5147	n/a
Ensembl	ENSG00000156973	n/a
UniProt	O43924 Q6IB24	n/a
RefSeq (mRNA)	NM_001291018 NM_002601	n/a
RefSeq (protein)	NP_001277947 NP_002592 NP_002592.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDE6D yw PDE6D a elwir hefyd yn Phosphodiesterase 6D a Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q37.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDE6D.

• PDED
• JBTS22

Llyfryddiaeth

• "Internalization and recycling of the human prostacyclin receptor is modulated through its isoprenylation-dependent interaction with the delta subunit of cGMP phosphodiesterase 6. ". J Biol Chem. 2006. PMID 16527812.
• "Cloning and gene structure of the rod cGMP phosphodiesterase delta subunit gene (PDED) in man and mouse. ". Eur J Hum Genet. 1998. PMID 9781033.
• "Prenylation defects in inherited retinal diseases. ". J Med Genet. 2014. PMID 24401286.
• "Identification of PDE6D as a molecular target of anecortave acetate via a methotrexate-anchored yeast three-hybrid screen. ". ACS Chem Biol. 2013. PMID 23301619.
• "cDNA sequence, genomic organization and mapping of PDE6D, the human gene encoding the delta subunit of the cGMP phosphodiesterase of retinal rod cells to chromosome 2q36.". Cytogenet Cell Genet. 1997. PMID 9533031.