PDCD6IP

PDCD6IP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OEV, 2OEW, 2OEX, 2OJQ, 2R02, 2R03, 2R05, 2XS1, 2XS8, 2ZNE, 3C3O, 3C3Q, 3C3R, 3E1R, 3WUV, 4JJY
Dynodwyr
Cyfenwau	PDCD6IP, AIP1, ALIX, DRIP4, HP95, programmed cell death 6 interacting protein
Dynodwyr allanol	OMIM: 608074 HomoloGene: 22614 GeneCards: PDCD6IP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • protein dimerization activity • proteinase activated receptor binding • calcium-dependent protein binding Cydrannau o'r gell • immunological synapse • focal adhesion • microtubule organizing center • extracellular vesicle • endoplasmic reticulum exit site • extracellular region • myelin sheath • Cytosgerbwd • melanosome • bilen • extracellular exosome • cytoplasm • cytosol • actomyosin • bicellular tight junction • cell junction • Flemming body Prosesau biolegol • cell cycle • mitotic metaphase plate congression • protein transport • positive regulation of exosomal secretion • GO:0019067 viral life cycle • regulation of mitotic spindle assembly • ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway • positive regulation of extracellular exosome assembly • septum digestion after cytokinesis • regulation of centrosome duplication • nucleus organization • multivesicular body assembly • regulation of extracellular exosome assembly • GO:0097285 apoptotic process • Cellraniad • viral budding via host ESCRT complex • GO:0022415 viral process • actomyosin contractile ring assembly • maintenance of epithelial cell apical/basal polarity • bicellular tight junction assembly • regulation of membrane permeability • mitotic cytokinesis • viral budding • protein homooligomerization • GO:0015915 transport • midbody abscission Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10015	n/a
Ensembl	ENSG00000170248	n/a
UniProt	Q8WUM4	n/a
RefSeq (mRNA)	NM_001162429 NM_001256192 NM_013374	n/a
RefSeq (protein)	NP_001155901 NP_001243121 NP_037506	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDCD6IP yw PDCD6IP a elwir hefyd yn Programmed cell death 6 interacting protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p22.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDCD6IP.

• AIP1
• ALIX
• HP95
• DRIP4

Llyfryddiaeth

• "Association between Programmed Cell Death 6 Interacting Protein Insertion/Deletion Polymorphism and the Risk of Breast Cancer in a Sample of Iranian Population. ". Dis Markers. 2015. PMID 26063962.
• "The programmed cell death 6 interacting protein insertion/deletion polymorphism is associated with non-small cell lung cancer risk in a Chinese Han population. ". Tumour Biol. 2014. PMID 24870593.
• "The role of Alix in the proliferation of human glioma cells. ". Hum Pathol. 2016. PMID 26980041.
• "Role of Alix in miRNA packaging during extracellular vesicle biogenesis. ". Int J Mol Med. 2016. PMID 26935291.
• "Phosphorylation-Dependent Activation of the ESCRT Function of ALIX in Cytokinetic Abscission and Retroviral Budding.". Dev Cell. 2016. PMID 26859355.