PCMT1

PCMT1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1I1N, 1KR5
Dynodwyr
Cyfenwau	PCMT1, PIMT, protein-L-isoaspartate (D-aspartate) O-methyltransferase
Dynodwyr allanol	OMIM: 176851 HomoloGene: 55895 GeneCards: PCMT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0102674, GO:0102675 methyltransferase activity • transferase activity • GO:0001948, GO:0016582 protein binding • protein-L-isoaspartate (D-aspartate) O-methyltransferase activity • cadherin binding Cydrannau o'r gell • extracellular vesicle • extracellular exosome • cytoplasm • cytosol Prosesau biolegol • methylation • protein repair • protein methylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5110	n/a
Ensembl	ENSG00000120265	n/a
UniProt	P22061	n/a
RefSeq (mRNA)	NM_001252049 NM_001252050 NM_001252051 NM_001252052 NM_001252053 NM_005389 NM_001360452 NM_001360456	n/a
RefSeq (protein)	NP_001238978 NP_001238979 NP_001238980 NP_001238981 NP_001238982 NP_005380 NP_001347381 NP_001347385	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PCMT1 yw PCMT1 a elwir hefyd yn Protein-L-isoaspartate (D-aspartate) O-methyltransferase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q25.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PCMT1.

• PIMT

Llyfryddiaeth

• "Protein L-isoaspartyl methyltransferase regulates p53 activity. ". Nat Commun. 2012. PMID 22735455.
• "Maternal PCMT1 gene polymorphisms and the risk of neural tube defects in a Chinese population of Lvliang high-risk area. ". Gene. 2012. PMID 22647835.
• "Polymorphic Variants of Human Protein l-Isoaspartyl Methyltransferase Affect Catalytic Activity, Aggregation, and Thermal Stability: IMPLICATIONS FOR THE ETIOLOGY OF NEUROLOGICAL DISORDERS AND COGNITIVE AGING. ". J Biol Chem. 2017. PMID 28100787.
• "Chaperone protein L-isoaspartate (D-aspartyl) O-methyltransferase as a novel predictor of poor prognosis in lung adenocarcinoma. ". Hum Pathol. 2016. PMID 26997432.
• "The protein l-isoaspartyl (d-aspartyl) methyltransferase protects against dopamine-induced apoptosis in neuroblastoma SH-SY5Y cells.". Neuroscience. 2015. PMID 25800307.