PBX3

PBX3
Dynodwyr
Cyfenwau	PBX3, PBX homeobox 3
Dynodwyr allanol	OMIM: 176312 HomoloGene: 21243 GeneCards: PBX3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • sequence-specific DNA binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cnewyllyn cell • transcription regulator complex Prosesau biolegol • regulation of respiratory gaseous exchange by nervous system process • adult locomotory behavior • anterior compartment pattern formation • dorsal spinal cord development • neuron development • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • posterior compartment specification • respiratory gaseous exchange by respiratory system • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5090	n/a
Ensembl	ENSG00000167081	n/a
UniProt	P40426 Q96AL5	n/a
RefSeq (mRNA)	NM_001134778 NM_006195 NM_001330782	n/a
RefSeq (protein)	NP_001128250 NP_001317711 NP_006186 NP_006186.1	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PBX3 yw PBX3 a elwir hefyd yn Pre-B-cell leukemia transcription factor 3 a PBX homeobox 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q33.3.

Llyfryddiaeth

• "Non-synonymous variants in pre-B cell leukemia homeobox (PBX) genes are associated with congenital heart defects. ". Eur J Med Genet. 2012. PMID 22426282.
• "Regulation of PBX3 expression by androgen and Let-7d in prostate cancer. ". Mol Cancer. 2011. PMID 21548940.
• "PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia. ". Int J Cancer. 2017. PMID 28411381.
• "PBX3 is a putative biomarker of aggressive prostate cancer. ". Int J Cancer. 2016. PMID 27273830.
• "PBX3 is overexpressed in gastric cancer and regulates cell proliferation.". Tumour Biol. 2014. PMID 24375258.