PASK

PASK
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1LL8, 3DLS
Dynodwyr
Cyfenwau	PASK, PASKIN, STK37, PAS domain containing serine/threonine kinase
Dynodwyr allanol	OMIM: 607505 HomoloGene: 9038 GeneCards: PASK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • kinase activity • transferase activity • nucleotide binding • protein kinase activity • GO:0001948, GO:0016582 protein binding • ATP binding • phosphatidylinositol binding • lipid binding • protein serine/threonine kinase activity Cydrannau o'r gell • cnewyllyn cell • cytosol • cytoplasm Prosesau biolegol • regulation of respiratory gaseous exchange • protein autophosphorylation • negative regulation of glycogen biosynthetic process • positive regulation of translation • regulation of glucagon secretion • phosphorylation • protein phosphorylation • energy homeostasis • GO:0007243 intracellular signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23178	n/a
Ensembl	ENSG00000115687	n/a
UniProt	Q96RG2	n/a
RefSeq (mRNA)	NM_001252119 NM_001252120 NM_001252122 NM_001252124 NM_015148	n/a
RefSeq (protein)	NP_001239048 NP_001239049 NP_001239051 NP_001239053 NP_055963	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PASK yw PASK a elwir hefyd yn PAS domain containing serine/threonine kinase a PAS domain-containing serine/threonine-protein kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q37.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PASK.

• STK37
• PASKIN

Llyfryddiaeth

• "PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase. ". Proc Natl Acad Sci U S A. 2001. PMID 11459942.
• "Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions. ". Biochem J. 2013. PMID 23721480.
• "The role of PAS kinase in PASsing the glucose signal. ". Sensors (Basel). 2010. PMID 22219681.
• "Per-arnt-sim (PAS) domain kinase (PASK) as a regulator of glucagon secretion. ". Diabetologia. 2011. PMID 21327866.
• "Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation.". Structure. 2002. PMID 12377121.