PAK4

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P21 (RAC1) activated kinase 4
Dynodwyr
CyfenwauPAK-4PAK4p21-activated kinase 4p21(CDKN1A)-activated kinase 4protein kinase related to S. cerevisiae STE20effector for Cdc42Hsserine/threonine-protein kinase PAK 4p21 protein (Cdc42/Rac)-activated kinase 4
Dynodwyr allanolGeneCards: [1]
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Lleoliad (UCSC)n/an/a
PubMed searchn/an/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PAK4 yw PAK4 a elwir hefyd yn P21 (RAC1) activated kinase 4 a Serine/threonine-protein kinase PAK 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.2.[1]

Llyfryddiaeth[golygu | golygu cod y dudalen]

  • "Prognostic significance of PAK4 expression in gastric cancer. ". J Clin Pathol. 2016. PMID 26614788.
  • "PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway. ". Diagn Pathol. 2015. PMID 26411419.
  • "Activated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling. ". Oncotarget. 2017. PMID 28407679.
  • "Functional role and therapeutic targeting of p21-activated kinase 4 in multiple myeloma. ". Blood. 2017. PMID 28096095.
  • "The P21-activated kinase PAK4 is implicated in fatty-acid potentiation of insulin secretion downstream of free fatty acid receptor 1.". Islets. 2016. PMID 27700527.

Cyfeiriadau[golygu | golygu cod y dudalen]