PAFAH1B2

PAFAH1B2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1VYH
Dynodwyr
Cyfenwau	PAFAH1B2, HEL-S-303, platelet activating factor acetylhydrolase 1b catalytic subunit 2
Dynodwyr allanol	OMIM: 602508 HomoloGene: 1932 GeneCards: PAFAH1B2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • 1-alkyl-2-acetylglycerophosphocholine esterase activity • platelet-activating factor acetyltransferase activity • hydrolase activity • protein homodimerization activity • protein heterodimerization activity • phospholipase A2 activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • Cellbilen • nucleolus • extracellular exosome • fibrillar center • extracellular region • cytoplasm • cytosol • secretory granule lumen • ficolin-1-rich granule lumen Prosesau biolegol • lipid catabolic process • positive regulation of macroautophagy • brain development • spermatogenesis • lipid metabolism • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5049	n/a
Ensembl	ENSG00000168092	n/a
UniProt	P68402	n/a
RefSeq (mRNA)	NM_001184746 NM_001184747 NM_001184748 NM_001309431 NM_002572	n/a
RefSeq (protein)	NP_001171675 NP_001171676 NP_001171677 NP_001296360 NP_002563	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PAFAH1B2 yw PAFAH1B2 a elwir hefyd yn Platelet activating factor acetylhydrolase 1b catalytic subunit 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PAFAH1B2.

• HEL-S-303

Llyfryddiaeth

• "Associations of platelet-activating factor acetylhydrolase (PAF-AH) gene polymorphisms with circulating PAF-AH levels and risk of coronary heart disease or blood stasis syndrome in the Chinese Han population.". Mol Biol Rep. 2014. PMID 25034894.
• "Plasma platelet-activating factor-acetyl hydrolase activity and the levels of free forms of biomarker of lipid peroxidation in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.". Neurosurgery. 2012. PMID 21866060.
• "Novel isoforms of intracellular platelet activating factor acetylhydrolase (PAFAH1b2) in human testis; encoded by alternatively spliced mRNAs. ". Prostaglandins Other Lipid Mediat. 2008. PMID 18155631.
• "Exclusion of the alpha2 subunit of platelet-activating factor acetylhydrolase 1b (PAFAH1B2) as a prothrombotic gene in a protein C-deficient kindred and population-based case-control sample.". Thromb Haemost. 2007. PMID 17849047.
• "Activity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.". ACS Chem Biol. 2015. PMID 25945974.