PADI4

PADI4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WD8, 1WD9, 1WDA, 2DEW, 2DEX, 2DEY, 2DW5, 3APM, 3APN, 3B1T, 3B1U, 4DKT, 4X8C, 4X8G
Dynodwyr
Cyfenwau	PADI4, PAD, PAD4, PADI5, PDI4, PDI5, peptidyl arginine deiminase 4
Dynodwyr allanol	OMIM: 605347 HomoloGene: 7883 GeneCards: PADI4
EC number	3.5.3.15
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • arginine deiminase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • protein-arginine deiminase activity • calcium ion binding • arginine binding • protein homodimerization activity Cydrannau o'r gell • nucleoplasm • cnewyllyn cell • cytosol • cytoplasm • GO:0009327 protein-containing complex Prosesau biolegol • chromatin remodeling • nucleosome assembly • GO:0009373 regulation of transcription, DNA-templated • immune system process • transcription, DNA-templated • stem cell population maintenance • innate immune response • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization • arginine deiminase pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23569	n/a
Ensembl	ENSG00000280908 ENSG00000159339	n/a
UniProt	Q9UM07	n/a
RefSeq (mRNA)	NM_012387	n/a
RefSeq (protein)	NP_036519	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PADI4 yw PADI4 a elwir hefyd yn Peptidyl arginine deiminase 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p36.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PADI4.

• PAD
• PAD4
• PDI4
• PDI5
• PADI5

Llyfryddiaeth

• "Association between the PADI4 -94G/A polymorphism and rheumatoid arthritis: a meta-analysis in the Chinese population. ". Genet Mol Res. 2016. PMID 27051025.
• "A novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells. ". Oncotarget. 2016. PMID 26673819.
• "Meta-analysis of the association between PADI4 -92C/G polymorphism and rheumatoid arthritis in the Chinese population. ". Braz J Med Biol Res. 2017. PMID 28832760.
• "PADI4 Epigenetically Suppresses p21 Transcription and Inhibits Cell Apoptosis in Fibroblast-like Synoviocytes from Rheumatoid Arthritis Patients. ". Int J Biol Sci. 2017. PMID 28367100.
• "Association between peptidyl arginine deiminase 4 (PADI4)-104C/T polymorphism and rheumatoid arthritis: a meta-analysis in the Chinese population.". Genet Mol Res. 2016. PMID 27706751.