OXSR1

OXSR1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2V3S, 2VWI, 3DAK
Dynodwyr
Cyfenwau	OXSR1, OSR1, oxidative stress responsive 1, oxidative stress responsive kinase 1
Dynodwyr allanol	OMIM: 604046 HomoloGene: 31288 GeneCards: OXSR1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • magnesium ion binding • protein kinase activity • GO:0001948, GO:0016582 protein binding • kinase activity • metal ion binding • nucleotide binding • transferase activity • ATP binding • protein serine/threonine kinase activity • identical protein binding • protein kinase binding Cydrannau o'r gell • extracellular exosome • cytoplasm • cytosol Prosesau biolegol • GO:0001306 response to oxidative stress • negative regulation of potassium ion transmembrane transport • cellular hypotonic response • phosphorylation • negative regulation of potassium ion transmembrane transporter activity • protein phosphorylation • peptidyl-threonine phosphorylation • GO:0007243 intracellular signal transduction • regulation of mitotic cell cycle • GO:0072468 signal transduction • stress-activated protein kinase signaling cascade • activation of protein kinase activity • regulation of apoptotic process • osmosensory signaling pathway • positive regulation of T cell chemotaxis • chemokine (C-C motif) ligand 21 signaling pathway • chemokine (C-X-C motif) ligand 12 signaling pathway • protein autophosphorylation • cellular response to chemokine Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9943	n/a
Ensembl	ENSG00000172939	n/a
UniProt	O95747	n/a
RefSeq (mRNA)	NM_005109	n/a
RefSeq (protein)	NP_005100	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn OXSR1 yw OXSR1 a elwir hefyd yn Oxidative stress responsive 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn OXSR1.

• OSR1

Llyfryddiaeth

• "Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers. ". Am J Physiol Cell Physiol. 2012. PMID 23034389.
• "STK39 is an independent risk factor for male hypertension in Han Chinese. ". Int J Cardiol. 2012. PMID 20889219.
• "Crystal structure of domain-swapped STE20 OSR1 kinase domain. ". Protein Sci. 2009. PMID 19177573.
• "Structure of the OSR1 kinase, a hypertension drug target. ". Proteins. 2008. PMID 18831043.
• "Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3.". J Hum Genet. 1999. PMID 10083736.