OLR1

OLR1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YPO, 1YPQ, 1YPU, 1YXJ, 1YXK, 3VLG
Dynodwyr
Cyfenwau	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, oxidized low density lipoprotein receptor 1
Dynodwyr allanol	OMIM: 602601 HomoloGene: 1910 GeneCards: OLR1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • carbohydrate binding • identical protein binding Cydrannau o'r gell • integral component of membrane • bilen • intracellular membrane-bounded organelle • receptor complex • Cellbilen • integral component of plasma membrane • nucleoplasm • extracellular region • membrane raft • specific granule membrane • tertiary granule membrane Prosesau biolegol • immune system process • blood circulation • proteolysis • cell adhesion • inflammatory response • leukocyte migration • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4973	n/a
Ensembl	ENSG00000173391	n/a
UniProt	P78380	n/a
RefSeq (mRNA)	NM_001172632 NM_001172633 NM_002543	n/a
RefSeq (protein)	NP_001166103 NP_001166104 NP_002534	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn OLR1 yw OLR1 a elwir hefyd yn Oxidized low-density lipoprotein receptor 1 ac Oxidized low density lipoprotein receptor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12p13.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn OLR1.

• LOX1
• LOXIN
• SLOX1
• CLEC8A
• SCARE1

Llyfryddiaeth

• "Scavenger Receptor LOX1 Genotype Predicts Coronary Artery Disease in Patients With Familial Hypercholesterolemia. ". Can J Cardiol. 2017. PMID 28941610.
• "LOX-1: A potential target for therapy in atherosclerosis; an in vitro study. ". Int J Biochem Cell Biol. 2017. PMID 28860004.
• "Multiple molecular dynamics simulations of human LOX-1 and Trp150Ala mutant reveal the structural determinants causing the full deactivation of the receptor. ". Proteins. 2017. PMID 28657156.
• "Novel role of the nutraceutical bioactive compound berberine in lectin-like OxLDL receptor 1-mediated endothelial dysfunction in comparison to lovastatin. ". Nutr Metab Cardiovasc Dis. 2017. PMID 28511903.
• "Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels in patients with restless legs syndrome.". Bratisl Lek Listy. 2016. PMID 27546362.