ODC1

ODC1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OO0, 4ZGY, 5BWA, 1D7K, 2ON3
Dynodwyr
Cyfenwau	ODC1, ODC, ornithine decarboxylase 1, NEDBIA, BABS, NEDBA
Dynodwyr allanol	OMIM: 165640 HomoloGene: 1906 GeneCards: ODC1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ornithine decarboxylase activity • GO:0001948, GO:0016582 protein binding • protein homodimerization activity • carboxy-lyase activity • catalytic activity • lyase activity Cydrannau o'r gell • perinuclear region of cytoplasm • cytosol • cytoplasm • cydran cellog Prosesau biolegol • putrescine biosynthetic process • polyamine biosynthetic process • response to virus • polyamine metabolic process • regulation of cellular amino acid metabolic process • positive regulation of cell population proliferation • kidney development • GO:1903362 regulation of protein catabolic process • putrescine biosynthetic process from ornithine Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4953	n/a
Ensembl	ENSG00000115758	n/a
UniProt	P11926	n/a
RefSeq (mRNA)	NM_002539 NM_001287188 NM_001287189 NM_001287190	n/a
RefSeq (protein)	NP_001274117 NP_001274118 NP_001274119 NP_002530	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ODC1 yw ODC1 a elwir hefyd yn Ornithine decarboxylase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2p25.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ODC1.

• ODC

Llyfryddiaeth

• "Targeting ODC1 inhibits tumor growth through reduction of lipid metabolism in human hepatocellular carcinoma.". Biochem Biophys Res Commun. 2016. PMID 27592554.
• "Suppression of ornithine decarboxylase promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. ". FEBS Lett. 2015. PMID 26140984.
• "Downregulation of tumstatin expression by overexpression of ornithine decarboxylase.". Oncol Rep. 2013. PMID 24002681.
• "Metabolic profiling of Alzheimer's disease brains.". Sci Rep. 2013. PMID 23917584.
• "Variants downstream of the ornithine decarboxylase gene influence risk of colorectal adenoma and aspirin chemoprevention.". Cancer Prev Res (Phila). 2011. PMID 21930798.