OBSL1

OBSL1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2CPC, 2E6P, 2E6Q, 2LU7, 2LVC, 2WP3, 2WWK, 2WWM, 3KNB
Dynodwyr
Cyfenwau	OBSL1, obscurin like 1, obscurin like cytoskeletal adaptor 1
Dynodwyr allanol	OMIM: 610991 HomoloGene: 28013 GeneCards: OBSL1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • cytoskeletal anchor activity • GO:0001948, GO:0016582 protein binding • structural constituent of muscle • actin filament binding • muscle alpha-actinin binding • structural molecule activity conferring elasticity Cydrannau o'r gell • Z disc • 3M complex • intercalated disc • M band • centrosome • microtubule organizing center • Cytosgerbwd • cytoplasm • Golgi apparatus • perinuclear region of cytoplasm • muscle myosin complex • cytosol • striated muscle thin filament • sarcomere Prosesau biolegol • protein localization to Golgi apparatus • cardiac myofibril assembly • microtubule cytoskeleton organization • cytoskeleton organization • regulation of mitotic nuclear division • positive regulation of dendrite morphogenesis • Golgi organization • striated muscle contraction • actin filament organization • sarcomere organization • striated muscle myosin thick filament assembly • post-translational protein modification • muscle contraction • skeletal muscle thin filament assembly • skeletal muscle myosin thick filament assembly • cardiac muscle tissue morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23363	n/a
Ensembl	ENSG00000124006	n/a
UniProt	O75147	n/a
RefSeq (mRNA)	NM_001173408 NM_001173431 NM_015311	n/a
RefSeq (protein)	NP_001166879 NP_001166902 NP_056126	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn OBSL1 yw OBSL1 a elwir hefyd yn Obscurin like 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q35.

Llyfryddiaeth

• "The Cytoskeletal Adaptor Obscurin-Like 1 Interacts with the Human Papillomavirus 16 (HPV16) Capsid Protein L2 and Is Required for HPV16 Endocytosis. ". J Virol. 2016. PMID 27654294.
• "Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection. ". Structure. 2017. PMID 27989621.
• "A Rare Cause of Short Stature: 3M Syndrome in a Patient with Novel Mutation in OBSL1 Gene. ". J Clin Res Pediatr Endocrinol. 2017. PMID 27796265.
• "Solution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the Human Cancer Protein Interaction Network. ". J Struct Funct Genomics. 2014. PMID 24989974.
• "The primordial growth disorder 3-M syndrome connects ubiquitination to the cytoskeletal adaptor OBSL1.". Am J Hum Genet. 2009. PMID 19481195.