NXF1

NXF1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4WYK, 1FO1, 1FT8, 1GO5, 1JKG, 1JN5, 1KOH, 1KOO, 1OAI, 2Z5K, 2Z5M, 3RW6, 3RW7
Dynodwyr
Cyfenwau	NXF1, MEX67, TAP, nuclear RNA export factor 1
Dynodwyr allanol	OMIM: 602647 HomoloGene: 38176 GeneCards: NXF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • single-stranded RNA binding • mRNA binding • GO:0005487 structural constituent of nuclear pore • nucleic acid binding • RNA binding Cydrannau o'r gell • cytoplasm • cytosol • nuclear speck • transcription export complex • nuclear pore • intracellular anatomical structure • nuclear inclusion body • cnewyllyn cell • nucleoplasm • nuclear envelope Prosesau biolegol • mRNA transport • mRNA export from nucleus • poly(A)+ mRNA export from nucleus • GO:0022415 viral process • RNA export from nucleus • GO:0015915 transport • protein transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10482	n/a
Ensembl	ENSG00000162231	n/a
UniProt	Q9UBU9	n/a
RefSeq (mRNA)	NM_006362 NM_001081491	n/a
RefSeq (protein)	NP_001074960 NP_006353	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NXF1 yw NXF1 a elwir hefyd yn Nuclear RNA export factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q12.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NXF1.

• TAP
• MEX67

Llyfryddiaeth

• "Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the cellular NXF1-p15 machinery. ". PLoS One. 2014. PMID 25360769.
• "Gammaretroviral pol sequences act in cis to direct polysome loading and NXF1/NXT-dependent protein production by gag-encoded RNA. ". Retrovirology. 2014. PMID 25212909.
• "Structure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAP. ". Nat Struct Mol Biol. 2011. PMID 21822283.
• "Head-to-tail intramolecular interaction of herpes simplex virus type 1 regulatory protein ICP27 is important for its interaction with cellular mRNA export receptor TAP/NXF1. ". MBio. 2010. PMID 21060739.
• "Individual influenza A virus mRNAs show differential dependence on cellular NXF1/TAP for their nuclear export.". J Gen Virol. 2010. PMID 20071484.