NUDT3

NUDT3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2FVV, 2Q9P
Dynodwyr
Cyfenwau	NUDT3, DIPP, DIPP-1, DIPP1, nudix hydrolase 3
Dynodwyr allanol	OMIM: 609228 HomoloGene: 31400 GeneCards: NUDT3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity • inositol diphosphate tetrakisphosphate diphosphatase activity • inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity • hydrolase activity • diphosphoinositol-polyphosphate diphosphatase activity • inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity • metal ion binding • inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity • inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity • magnesium ion binding • inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity • inositol diphosphate pentakisphosphate diphosphatase activity • inositol bisdiphosphate tetrakisphosphate diphosphatase activity • endopolyphosphatase activity • bis(5'-adenosyl)-hexaphosphatase activity • bis(5'-adenosyl)-pentaphosphatase activity • m7G(5')pppN diphosphatase activity Cydrannau o'r gell • cnewyllyn cell • cytoplasm • cytosol Prosesau biolegol • cell-cell signaling • diadenosine polyphosphate catabolic process • inositol phosphate metabolic process • diphosphoinositol polyphosphate catabolic process • diadenosine pentaphosphate catabolic process • diadenosine hexaphosphate catabolic process • adenosine 5'-(hexahydrogen pentaphosphate) catabolic process • diphosphoinositol polyphosphate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	11165	n/a
Ensembl	ENSG00000272325	n/a
UniProt	O95989	n/a
RefSeq (mRNA)	NM_006703	n/a
RefSeq (protein)	NP_006694	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NUDT3 yw NUDT3 a elwir hefyd yn Nudix hydrolase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NUDT3.

• DIPP
• DIPP1
• DIPP-1

Llyfryddiaeth

• "Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates. ". J Biol Chem. 1999. PMID 10585413.
• "The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein. ". J Biol Chem. 1999. PMID 10419486.
• "Nudt3 is an mRNA decapping enzyme that modulates cell migration. ". RNA. 2016. PMID 26932476.
• "NUDT3 rs206936 is associated with body mass index in obese Japanese women. ". Endocr J. 2013. PMID 23708086.
• "Crystal structure of human diphosphoinositol phosphatase 1.". Proteins. 2009. PMID 19585659.