NUDT11

NUDT11
Dynodwyr
Cyfenwau	NUDT11, APS1, ASP1, DIPP3b, DIPP3beta, hDIPP3beta, nudix hydrolase 11
Dynodwyr allanol	OMIM: 300528 HomoloGene: 86995 GeneCards: NUDT11
EC number	3.6.1.60
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity • inositol diphosphate tetrakisphosphate diphosphatase activity • inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity • hydrolase activity • metal ion binding • inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity • inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity • inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity • inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity • inositol diphosphate pentakisphosphate diphosphatase activity • inositol bisdiphosphate tetrakisphosphate diphosphatase activity • endopolyphosphatase activity • diphosphoinositol-polyphosphate diphosphatase activity • bis(5'-adenosyl)-hexaphosphatase activity • bis(5'-adenosyl)-pentaphosphatase activity • m7G(5')pppN diphosphatase activity Cydrannau o'r gell • intracellular anatomical structure • cnewyllyn cell • cytoplasm • cytosol Prosesau biolegol • inositol phosphate metabolic process • diphosphoinositol polyphosphate metabolic process • diadenosine pentaphosphate catabolic process • diadenosine hexaphosphate catabolic process • adenosine 5'-(hexahydrogen pentaphosphate) catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	55190	n/a
Ensembl	ENSG00000196368	n/a
UniProt	Q96G61	n/a
RefSeq (mRNA)	NM_018159	n/a
RefSeq (protein)	NP_060629	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NUDT11 yw NUDT11 a elwir hefyd yn Nudix hydrolase 11 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xp11.22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NUDT11.

• APS1
• ASP1
• DIPP3b
• DIPP3beta
• hDIPP3beta

Llyfryddiaeth

• "Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. ". Nat Genet. 2008. PMID 18264098.
• "Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate. ". J Biol Chem. 2002. PMID 12370170.
• "An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase. ". J Biol Chem. 2002. PMID 12105228.
• "Genetic and functional analyses implicate the NUDT11, HNF1B, and SLC22A3 genes in prostate cancer pathogenesis. ". Proc Natl Acad Sci U S A. 2012. PMID 22730461.
• "Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.". BMC Biochem. 2002. PMID 12121577.