NR4A3

NR4A3
Dynodwyr
Cyfenwau	NR4A3, CHN, CSMF, MINOR, NOR1, TEC, nuclear receptor subfamily 4 group A member 3
Dynodwyr allanol	OMIM: 600542 HomoloGene: 5074 GeneCards: NR4A3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • sequence-specific DNA binding • protein homodimerization activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • zinc ion binding • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • metal ion binding • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • steroid hormone receptor activity • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity • core promoter sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • histone acetyltransferase binding • glucocorticoid receptor binding • transcription coactivator binding • protein kinase binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • cAMP response element binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding Cydrannau o'r gell • transcription regulator complex • mast cell granule • nucleoplasm • cnewyllyn cell Prosesau biolegol • GO:1904089 negative regulation of neuron apoptotic process • cellular response to catecholamine stimulus • semicircular canal morphogenesis • GO:0009373 regulation of transcription, DNA-templated • neuromuscular process controlling balance • positive regulation of epithelial cell proliferation • common myeloid progenitor cell proliferation • pyruvate oxidation • negative regulation of oxidative stress-induced neuron death • mesoderm formation • response to peptide hormone • negative regulation of apoptotic process • positive regulation of leukocyte apoptotic process • GO:1901227 negative regulation of transcription by RNA polymerase II • regulation of smooth muscle cell proliferation • cellular response to leptin stimulus • transcription, DNA-templated • positive regulation of cardiac muscle hypertrophy • axon guidance • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • adult behavior • positive regulation of cell cycle • negative regulation of hydrogen peroxide-induced neuron death • gastrulation • positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway • animal organ regeneration • inner ear morphogenesis • positive regulation of mast cell cytokine production • Resbiradaeth cellog • vestibular reflex • energy homeostasis • cellular response to corticotropin-releasing hormone stimulus • mast cell degranulation • transcription initiation from RNA polymerase II promoter • positive regulation of feeding behavior • positive regulation of glucose transmembrane transport • hippocampus development • positive regulation of monocyte aggregation • fat cell differentiation • response to hydrogen peroxide • regulation of type B pancreatic cell proliferation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • steroid hormone mediated signaling pathway • positive regulation of smooth muscle cell proliferation • positive regulation of fatty acid oxidation • intracellular receptor signaling pathway • regulation of megakaryocyte differentiation • platelet-derived growth factor receptor signaling pathway • positive regulation of vascular associated smooth muscle cell proliferation • positive regulation of vascular associated smooth muscle cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8013	n/a
Ensembl	ENSG00000119508	n/a
UniProt	Q92570	n/a
RefSeq (mRNA)	NM_006981 NM_173198 NM_173199 NM_173200	n/a
RefSeq (protein)	NP_008912 NP_775291 NP_775292	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NR4A3 yw NR4A3 a elwir hefyd yn Nuclear receptor subfamily 4 group A member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9q31.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NR4A3.

• CHN
• TEC
• CSMF
• NOR1
• MINOR

Llyfryddiaeth

• "The nuclear receptor NOR-1/NR4A3 regulates the multifunctional glycoprotein vitronectin in human vascular smooth muscle cells. ". FASEB J. 2017. PMID 28666984.
• "NOR1 promotes hepatocellular carcinoma cell proliferation and migration through modulating the Notch signaling pathway. ". Exp Cell Res. 2017. PMID 28232113.
• "Possible role of intragenic DNA hypermethylation in gene silencing of the tumor suppressor gene NR4A3 in acute myeloid leukemia. ". Leuk Res. 2016. PMID 27697661.
• "Localization of nuclear receptor subfamily 4, group A, member 3 (NR4A3) in Lewy body disease and multiple system atrophy. ". Neuropathology. 2015. PMID 26096603.
• "The neuron-derived orphan receptor 1 (NOR1) is induced upon human alternative macrophage polarization and stimulates the expression of markers of the M2 phenotype.". Atherosclerosis. 2015. PMID 25941992.