NQO2

NQO2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1QR2, 1SG0, 1XI2, 1ZX1, 2BZS, 2QMY, 2QMZ, 2QR2, 2QWX, 2QX4, 2QX6, 2QX8, 2QX9, 3FW1, 3G5M, 3GAM, 3NFR, 3NHF, 3NHJ, 3NHK, 3NHL, 3NHP, 3NHR, 3NHS, 3NHU, 3NHW, 3NHY, 3O2N, 3O73, 3OVM, 3OWH, 3OWX, 3OX1, 3OX2, 3OX3, 3TE7, 3TEM, 3TZB, 3UXE, 3UXH, 4FGJ, 4FGK, 4FGL, 4GQI, 4GR9, 4QOD, 4QOE, 4QOF, 4QOG, 4QOH, 4QOI, 4QOJ, 4U7F, 4U7G, 4U7H, 4XDG, 4XDH, 4ZVL, 4ZVM, 4ZVK, 5LBT, 5LBU, 5BUC, 4ZVN
Dynodwyr
Cyfenwau	NQO2, Nqo2, NMO2, Nmor2, Ox2, DHQV, DIA6, QR2, NAD(P)H quinone dehydrogenase 2, N-ribosyldihydronicotinamide:quinone reductase 2
Dynodwyr allanol	OMIM: 160998 HomoloGene: 696 GeneCards: NQO2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • dihydronicotinamide riboside quinone reductase activity • zinc ion binding • electron transfer activity • oxidoreductase activity • oxidoreductase activity, acting on other nitrogenous compounds as donors • chloride ion binding • protein homodimerization activity • FAD binding • melatonin binding • resveratrol binding • NAD(P)H dehydrogenase (quinone) activity Cydrannau o'r gell • extracellular exosome • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • Cof • positive regulation of neuron apoptotic process • positive regulation of vascular associated smooth muscle cell proliferation • positive regulation of ERK1 and ERK2 cascade • positive regulation of reactive oxygen species metabolic process • xenobiotic metabolic process • electron transport chain Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4835	n/a
Ensembl	ENSG00000124588	n/a
UniProt	P16083	n/a
RefSeq (mRNA)	NM_000904 NM_001290221 NM_001290222 NM_001318940	n/a
RefSeq (protein)	NP_000895 NP_001277150 NP_001277151 NP_001305869	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NQO2 yw NQO2 a elwir hefyd yn N-ribosyldihydronicotinamide:quinone reductase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p25.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NQO2.

• QR2
• DHQV
• DIA6
• NMOR2

Llyfryddiaeth

• "The ontogeny and population variability of human hepatic dihydronicotinamide riboside:quinone oxidoreductase (NQO2). ". J Biochem Mol Toxicol. 2017. PMID 28346733.
• "Expression of Quinone Reductase-2 in the Cortex Is a Muscarinic Acetylcholine Receptor-Dependent Memory Consolidation Constraint. ". J Neurosci. 2015. PMID 26609153.
• "The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties. ". FEBS Lett. 2014. PMID 24631540.
• "Chloroquine binding reveals flavin redox switch function of quinone reductase 2. ". J Biol Chem. 2013. PMID 23471972.
• "Increased hippocampal quinone reductase 2 in Alzheimer's disease.". Neurosci Lett. 2011. PMID 21803122.