NOVA1

NOVA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1DT4, 2ANN, 2ANR
Dynodwyr
Cyfenwau	NOVA1, Nova-1, NOVA alternative splicing regulator 1
Dynodwyr allanol	OMIM: 602157 HomoloGene: 21296 GeneCards: NOVA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleic acid binding • mRNA binding • RNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • nucleolus • intracellular membrane-bounded organelle • cnewyllyn cell Prosesau biolegol • mRNA splicing, via spliceosome • GO:0033168, GO:0036404, GO:1902360 RNA processing • locomotory behavior • RNA splicing • regulation of RNA metabolic process • chemical synaptic transmission • negative regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4857	n/a
Ensembl	ENSG00000139910	n/a
UniProt	P51513	n/a
RefSeq (mRNA)	NM_002515 NM_006489 NM_006491	n/a
RefSeq (protein)	NP_002506 NP_006480 NP_006482 NP_001353319 NP_001353320 NP_001353321 NP_001353322 NP_001353323 NP_001353324 NP_001353325 NP_001353326 NP_001353327	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NOVA1 yw NOVA1 a elwir hefyd yn RNA-binding protein Nova-1 a NOVA alternative splicing regulator 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 14, band 14q12.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NOVA1.

• Nova-1

Llyfryddiaeth

• "Implications of NOVA1 suppression within the microenvironment of gastric cancer: association with immune cell dysregulation. ". Gastric Cancer. 2017. PMID 27318497.
• "MiR-181b-5p downregulates NOVA1 to suppress proliferation, migration and invasion and promote apoptosis in astrocytoma. ". PLoS One. 2014. PMID 25299073.
• "High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma. ". PLoS One. 2014. PMID 24608171.
• "Paraneoplastic antibody during follow-up of a patient with anti-Ri-associated paraneoplastic neurological syndrome. ". Acta Neurol Scand. 2009. PMID 18822086.
• "The neuronal RNA binding protein Nova-1 recognizes specific RNA targets in vitro and in vivo.". Mol Cell Biol. 1997. PMID 9154818.