NOS1

NOS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4D1N, 4UCH, 4UH5, 4UH6, 4V3U, 5ADF, 5ADG, 5ADI, 5FVX, 5FVW, 5FVU, 5FVV
Dynodwyr
Cyfenwau	NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS, nitric oxide synthase 1
Dynodwyr allanol	OMIM: 163731 HomoloGene: 37327 GeneCards: NOS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transmembrane transporter binding • tetrahydrobiopterin binding • NADP binding • cadmium ion binding • FMN binding • metal ion binding • heme binding • oxidoreductase activity • scaffold protein binding • calmodulin binding • GO:0001948, GO:0016582 protein binding • sodium channel regulator activity • flavin adenine dinucleotide binding • arginine binding • nitric-oxide synthase activity • NADPH-hemoprotein reductase activity Cydrannau o'r gell • bilen • photoreceptor inner segment • T-tubule • synapse • ryanodine receptor complex • mitocondria • perinuclear region of cytoplasm • caveola • Cytosgerbwd • cell projection • dendritic spine • Z disc • sarcoplasmic reticulum membrane • membrane raft • sarcoplasmic reticulum • sarcolemma • cytosol • cytoplasm • nucleoplasm • Cellbilen • GO:0009327 protein-containing complex • calyx of Held • cnewyllyn cell • vesicle membrane • GO:0097483, GO:0097481 postsynaptic density Prosesau biolegol • multicellular organismal response to stress • positive regulation of guanylate cyclase activity • regulation of sodium ion transport • positive regulation of the force of heart contraction • negative regulation of hydrolase activity • striated muscle contraction • regulation of neurogenesis • negative regulation of serotonin uptake • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • peptidyl-cysteine S-nitrosylation • cell redox homeostasis • arginine catabolic process • negative regulation of potassium ion transport • nitric oxide mediated signal transduction • negative regulation of calcium ion transport into cytosol • myoblast fusion • regulation of calcium ion transmembrane transport via high voltage-gated calcium channel • regulation of ryanodine-sensitive calcium-release channel activity • regulation of cardiac conduction • nitric oxide biosynthetic process • positive regulation of sodium ion transmembrane transport • cellular response to growth factor stimulus • neurotransmitter biosynthetic process • positive regulation of histone acetylation • negative regulation of calcium ion transport • regulation of cardiac muscle contraction • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • response to hypoxia • response to heat • negative regulation of blood pressure • retrograde trans-synaptic signaling by nitric oxide • vasodilation • positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process • synaptic signaling by nitric oxide • response to hormone • response to lipopolysaccharide • positive regulation of peptidyl-serine phosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4842	n/a
Ensembl	ENSG00000089250	n/a
UniProt	P29475	n/a
RefSeq (mRNA)	NM_000620 NM_001204213 NM_001204214 NM_001204218	n/a
RefSeq (protein)	NP_000611 NP_001191142 NP_001191143 NP_001191147	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NOS1 yw NOS1 a elwir hefyd yn Nitric oxide synthase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q24.22.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NOS1.

• NOS
• bNOS
• nNOS
• IHPS1
• N-NOS
• NC-NOS

Llyfryddiaeth

• "The human coronary vasodilatory response to acute mental stress is mediated by neuronal nitric oxide synthase. ". Am J Physiol Heart Circ Physiol. 2017. PMID 28646032.
• "Neuronal nitric oxide synthase polymorphisms in obsessive-compulsive disorder. ". Nord J Psychiatry. 2017. PMID 27739347.
• "Improved method for assembly of hemeprotein neuronal NO-synthase heterodimers. ". Anal Biochem. 2016. PMID 27487179.
• "Human Ischemic Cardiomyopathy Shows Cardiac Nos1 Translocation and its Increased Levels are Related to Left Ventricular Performance. ". Sci Rep. 2016. PMID 27041589.
• "Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes.". Soc Cogn Affect Neurosci. 2016. PMID 26746182.