NME4

NME4
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1EHW
Dynodwyr
Cyfenwau	NME4, NDPK-D, NM23H4, nm23-H4, NME/NM23 nucleoside diphosphate kinase 4
Dynodwyr allanol	OMIM: 601818 HomoloGene: 3673 GeneCards: NME4
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • lipid binding • nucleotide binding • transferase activity • kinase activity • ATP binding • GO:0001948, GO:0016582 protein binding • nucleoside diphosphate kinase activity • cardiolipin binding Cydrannau o'r gell • mitochondrial matrix • bilen • mitochondrial inner membrane • mitocondria • intracellular anatomical structure • mitochondrial intermembrane space Prosesau biolegol • nucleobase-containing small molecule interconversion • nucleoside metabolic process • nucleoside diphosphate phosphorylation • GTP biosynthetic process • UTP biosynthetic process • CTP biosynthetic process • nucleotide metabolic process • phosphorylation • regulation of apoptotic process • lipid transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4833	n/a
Ensembl	ENSG00000103202	n/a
UniProt	O00746	n/a
RefSeq (mRNA)	NM_005009 NM_001286433 NM_001286435 NM_001286436 NM_001286438 NM_001286439 NM_001286440	n/a
RefSeq (protein)	NP_001273362 NP_001273364 NP_001273365 NP_001273367 NP_001273368 NP_001273369 NP_005000	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NME4 yw NME4 a elwir hefyd yn Nucleoside diphosphate kinase, mitochondrial a NME/NM23 nucleoside diphosphate kinase 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NME4.

• NDPK-D
• NM23H4
• nm23-H4

Llyfryddiaeth

• "Mitochondrial NM23-H4/NDPK-D: a bifunctional nanoswitch for bioenergetics and lipid signaling. ". Naunyn Schmiedebergs Arch Pharmacol. 2015. PMID 25231795.
• "nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13. ". Hum Genet. 1997. PMID 9099850.
• "The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase. ". J Biol Chem. 2000. PMID 10799505.
• "Structural comparison of highly similar nucleoside-diphosphate kinases: Molecular explanation of distinct membrane-binding behavior. ". Biochimie. 2014. PMID 25010650.
• "Dual function of mitochondrial Nm23-H4 protein in phosphotransfer and intermembrane lipid transfer: a cardiolipin-dependent switch.". J Biol Chem. 2013. PMID 23150663.