NEO1

NEO1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X5F, 1X5G, 1X5H, 1X5I, 1X5J, 1X5K, 3P4L, 4UI2
Dynodwyr
Cyfenwau	NEO1, IGDCC2, NGN, NTN1R2, neogenin 1
Dynodwyr allanol	OMIM: 601907 HomoloGene: 1870 GeneCards: NEO1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • co-receptor binding • GO:0001948, GO:0016582 protein binding • signaling receptor activity Cydrannau o'r gell • integral component of membrane • plasma membrane protein complex • Cellbilen • Golgi apparatus • integral component of plasma membrane • bilen • nucleoplasm Prosesau biolegol • positive regulation of BMP signaling pathway • iron ion homeostasis • cell adhesion • nervous system development • axon guidance • GO:0072468 signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4756	n/a
Ensembl	ENSG00000067141	n/a
UniProt	Q92859	n/a
RefSeq (mRNA)	NM_001172623 NM_001172624 NM_002499	n/a
RefSeq (protein)	NP_001166094 NP_001166095 NP_002490	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NEO1 yw NEO1 a elwir hefyd yn Neogenin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q24.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NEO1.

• NGN
• IGDCC2
• NTN1R2

Llyfryddiaeth

• "Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells. ". J Biol Chem. 2016. PMID 27288875.
• "Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension. ". Nat Commun. 2016. PMID 27029596.
• "Unmasking a novel disease gene NEO1 associated with autism spectrum disorders by a hemizygous deletion on chromosome 15 and a functional polymorphism. ". Behav Brain Res. 2016. PMID 26518331.
• "Overexpression of neogenin inhibits cell proliferation and induces apoptosis in human MDA-MB-231 breast carcinoma cells. ". Oncol Rep. 2015. PMID 25998984.
• "Neogenin expression is inversely associated with breast cancer grade in ex vivo.". World J Surg Oncol. 2014. PMID 25416629.