NDST1

NDST1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1NST
Dynodwyr
Cyfenwau	NDST1, HSST, NST1, MRT46, N-deacetylase/N-sulfotransferase 1, N-deacetylase and N-sulfotransferase 1
Dynodwyr allanol	OMIM: 600853 HomoloGene: 20386 GeneCards: NDST1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • sulfotransferase activity • deacetylase activity • catalytic activity • hydrolase activity • N-acetylglucosamine deacetylase activity • GO:0001948, GO:0016582 protein binding • [heparan sulfate-glucosamine N-sulfotransferase activity] • heparan sulfate N-acetylglucosaminyltransferase activity • heparan sulfate sulfotransferase activity Cydrannau o'r gell • integral component of membrane • Golgi apparatus • bilen • Golgi membrane Prosesau biolegol • cardiac septum development • heparin biosynthetic process • embryonic neurocranium morphogenesis • coronary vasculature development • respiratory gaseous exchange by respiratory system • fibroblast growth factor receptor signaling pathway • aorta development • heart development • glycosaminoglycan biosynthetic process • animal organ morphogenesis • embryonic viscerocranium morphogenesis • polysaccharide biosynthetic process • forebrain development • metabolaeth • protein sulfation • inflammatory response • midbrain development • glycosaminoglycan metabolic process • heparan sulfate proteoglycan biosynthetic process • heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process • positive regulation of MAPK cascade • positive regulation of smoothened signaling pathway • sulfur compound metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3340	n/a
Ensembl	ENSG00000070614	n/a
UniProt	P52848	n/a
RefSeq (mRNA)	NM_001301063 NM_001543	n/a
RefSeq (protein)	NP_001287992 NP_001534	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NDST1 yw NDST1 a elwir hefyd yn N-deacetylase and N-sulfotransferase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q33.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NDST1.

• HSST
• NST1
• MRT46

Llyfryddiaeth

• "A girl with developmental delay, ataxia, cranial nerve palsies, severe respiratory problems in infancy-Expanding NDST1 syndrome. ". Am J Med Genet A. 2017. PMID 28211985.
• "Role of Deacetylase Activity of N-Deacetylase/N-Sulfotransferase 1 in Forming N-Sulfated Domain in Heparan Sulfate. ". J Biol Chem. 2015. PMID 26109066.
• "MicroRNA-191 targets N-deacetylase/N-sulfotransferase 1 and promotes cell growth in human gastric carcinoma cell line MGC803. ". Acta Biochim Biophys Sin (Shanghai). 2011. PMID 21947487.
• "Altered expression of NDST-1 messenger RNA in puromycin aminonucleoside nephrosis. ". J Lab Clin Med. 2004. PMID 14966466.
• "Antibody-based assay for N-deacetylase activity of heparan sulfate/heparin N-deacetylase/N-sulfotransferase (NDST): novel characteristics of NDST-1 and -2.". Glycobiology. 2003. PMID 12634318.