MYOF

MYOF
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DMH, 2K2O
Dynodwyr
Cyfenwau	MYOF, FER1L3, myoferlin, HAE7
Dynodwyr allanol	OMIM: 604603 HomoloGene: 40882 GeneCards: MYOF
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • phospholipid binding Cydrannau o'r gell • caveola • integral component of membrane • Cellbilen • nuclear membrane • extracellular exosome • nuclear envelope • cytoplasmic vesicle membrane • GO:0016023 cytoplasmic vesicle • intracellular membrane-bounded organelle • cnewyllyn cell • bilen Prosesau biolegol • cellular response to heat • plasma membrane repair • muscle contraction • blood circulation • regulation of vascular endothelial growth factor receptor signaling pathway • myoblast fusion • glycerol metabolic process • T-tubule organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	26509	n/a
Ensembl	ENSG00000138119	n/a
UniProt	Q9NZM1	n/a
RefSeq (mRNA)	NM_013451 NM_133337	n/a
RefSeq (protein)	NP_038479 NP_579899	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MYOF yw MYOF a elwir hefyd yn Myoferlin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q23.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MYOF.

• FER1L3

Llyfryddiaeth

• "Myoferlin is a key regulator of EGFR activity in breast cancer. ". Cancer Res. 2013. PMID 23864327.
• "Myoferlin depletion in breast cancer cells promotes mesenchymal to epithelial shape change and stalls invasion. ". PLoS One. 2012. PMID 22761893.
• "High expression of myoferlin is associated with poor outcome in oropharyngeal squamous cell carcinoma patients and is inversely associated with HPV-status. ". Oncotarget. 2016. PMID 26919244.
• "Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer. ". Int J Cancer. 2016. PMID 26311411.
• "Myoferlin depletion elevates focal adhesion kinase and paxillin phosphorylation and enhances cell-matrix adhesion in breast cancer cells.". Am J Physiol Cell Physiol. 2015. PMID 25631868.