MYD88

MYD88
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JS7, 2Z5V, 3MOP, 4DOM, 4EO7
Dynodwyr
Cyfenwau	MYD88, MYD88D, myeloid differentiation primary response 88, innate immune signal transduction adaptor, MYD88 innate immune signal transduction adaptor, IMD68
Dynodwyr allanol	OMIM: 602170 HomoloGene: 1849 GeneCards: MYD88
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • death receptor binding • GO:0001948, GO:0016582 protein binding • TIR domain binding • identical protein binding • protein self-association • Toll-like receptor binding Cydrannau o'r gell • cytosol • Cellbilen • endosome membrane • cytoplasm • cnewyllyn cell Prosesau biolegol • response to interleukin-1 • immune system process • negative regulation of apoptotic process • MyD88-dependent toll-like receptor signaling pathway • toll-like receptor signaling pathway • cell surface receptor signaling pathway • cellular response to mechanical stimulus • regulation of inflammatory response • positive regulation of interleukin-6 production • positive regulation of I-kappaB kinase/NF-kappaB signaling • toll-like receptor 9 signaling pathway • positive regulation of interleukin-17 production • inflammatory response • 3'-UTR-mediated mRNA stabilization • positive regulation of type I interferon production • positive regulation of interleukin-23 production • GO:0072468 signal transduction • GO:0051637 defense response to Gram-positive bacterium • positive regulation of NF-kappaB transcription factor activity • GO:0097285 apoptotic process • innate immune response • type I interferon signaling pathway • GO:1901313 positive regulation of gene expression • positive regulation of interleukin-8 production • defense response to bacterium • interleukin-1-mediated signaling pathway • cellular response to oxidised low-density lipoprotein particle stimulus • positive regulation of cytokine production involved in inflammatory response • ffagocytosis • Toll signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4615	n/a
Ensembl	ENSG00000172936	n/a
UniProt	Q99836	n/a
RefSeq (mRNA)	NM_001172566 NM_001172567 NM_001172568 NM_001172569 NM_002468 NM_001365876 NM_001365877 NM_001374787 NM_001374788	n/a
RefSeq (protein)	NP_001166037 NP_001166038 NP_001166039 NP_001166040 NP_002459 NP_001352805 NP_001352806 NP_001361716 NP_001361717	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MYD88 yw MYD88 a elwir hefyd yn Myeloid differentiation primary response 88 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p22.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MYD88.

• MYD88D

Llyfryddiaeth

• "The role of N-terminal segment and membrane association in MyD88-mediated signaling. ". Biochem Biophys Res Commun. 2018. PMID 29155181.
• "Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas. ". Br J Ophthalmol. 2018. PMID 29122821.
• "The -938C>A Polymorphism in MYD88Is Associated with Susceptibility to Tuberculosis: A Pilot Study. ". Dis Markers. 2016. PMID 28127112.
• "Expression of MYD88 in Adipose Tissue of Obese People: Is There Some Role in the Development of Metabolic Syndrome?". Metab Syndr Relat Disord. 2017. PMID 28075222.
• "Genetic characterization of MYD88-mutated lymphoplasmacytic lymphoma in comparison with MYD88-mutated chronic lymphocytic leukemia.". Leukemia. 2017. PMID 27840426.