MXD1

MXD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1E91, 1G1E, 1NLW, 1PD7, 1S5Q
Dynodwyr
Cyfenwau	MXD1, BHLHC58, MAD, MAD1, MAX dimerization protein 1
Dynodwyr allanol	OMIM: 600021 HomoloGene: 1767 GeneCards: MXD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding • GO:0001104 transcription coregulator activity • protein dimerization activity • GO:0001106 transcription corepressor activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • mitocondria • cytosol Prosesau biolegol • multicellular organism development • cell population proliferation • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4084	n/a
Ensembl	ENSG00000059728	n/a
UniProt	Q05195	n/a
RefSeq (mRNA)	NM_002357 NM_001202513 NM_001202514	n/a
RefSeq (protein)	NP_001189442 NP_001189443 NP_002348	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MXD1 yw MXD1 a elwir hefyd yn MAX dimerization protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MXD1.

• MAD
• MAD1
• BHLHC58

Llyfryddiaeth

• "Effect of the transcriptional repressor Mad1 on proliferation of human melanoma cells. ". Exp Dermatol. 2002. PMID 12366697.
• "Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25. ". Genomics. 1994. PMID 7829091.
• "miR-382-5p Controls Hematopoietic Stem Cell Differentiation Through the Downregulation of MXD1. ". Stem Cells Dev. 2016. PMID 27520398.
• "TCP10L synergizes with MAD1 in transcriptional suppression and cell cycle arrest through mutual interaction. ". BMB Rep. 2016. PMID 26698869.
• "The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.". Mol Carcinog. 2009. PMID 19526459.