MTSS1

MTSS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D1K
Dynodwyr
Cyfenwau	MTSS1, MIM, MIMA, MIMB, metastasis suppressor 1, I-BAR domain containing, MTSS I-BAR domain containing 1
Dynodwyr allanol	OMIM: 608486 HomoloGene: 8841 GeneCards: MTSS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin monomer binding • GO:0001948, GO:0016582 protein binding • identical protein binding • actin binding • signaling receptor binding Cydrannau o'r gell • cytoplasm • ruffle • endocytic vesicle • actin cytoskeleton • Cytosgerbwd Prosesau biolegol • renal tubule morphogenesis • nephron tubule epithelial cell differentiation • transmembrane receptor protein tyrosine kinase signaling pathway • cellular response to fluid shear stress • cell adhesion • epithelial cell proliferation involved in renal tubule morphogenesis • microspike assembly • negative regulation of epithelial cell proliferation • plasma membrane organization • actin cytoskeleton organization • glomerulus morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9788	n/a
Ensembl	ENSG00000170873	n/a
UniProt	O43312	n/a
RefSeq (mRNA)	NM_001282971 NM_001282974 NM_014751 NM_001363294 NM_001363295 NM_001363296 NM_001363297 NM_001363298 NM_001363299 NM_001363300 NM_001363301 NM_001363302	n/a
RefSeq (protein)	NP_001269900 NP_001269903 NP_055566 NP_001350223 NP_001350224 NP_001350225 NP_001350226 NP_001350227 NP_001350228 NP_001350229 NP_001350230 NP_001350231	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MTSS1 yw MTSS1 a elwir hefyd yn Metastasis suppressor protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8q24.13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MTSS1.

• MIM
• MIMA
• MIMB

Llyfryddiaeth

• "Metastasis suppressor 1 expression in human ovarian cancer: The impact on cellular migration and metastasis. ". Int J Oncol. 2015. PMID 26316204.
• "Expression and Significances of MTSS1 in Pancreatic Cancer. ". Pathol Oncol Res. 2016. PMID 26198729.
• "Reduced Expression of Metastasis Suppressor-1 (MTSS1) Accelerates Progression of Human Bladder Uroepithelium Cell Carcinoma. ". Anticancer Res. 2017. PMID 28739745.
• "Loss of MTSS1 results in increased metastatic potential in pancreatic cancer. ". Oncotarget. 2017. PMID 28146435.
• "Effect of metastasis suppressor 1 on H1299 cells and its clinical significance in non-small cell lung cancer.". Oncol Rep. 2016. PMID 27634022.