MTRR

MTRR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2QTL, 2QTZ
Dynodwyr
Cyfenwau	MTRR, MSR, cblE, 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Dynodwyr allanol	OMIM: 602568 HomoloGene: 11419 GeneCards: MTRR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • FMN binding • NADPH-hemoprotein reductase activity • flavin adenine dinucleotide binding • FAD binding • GO:0001948, GO:0016582 protein binding • NADP binding • NADPH binding • oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor • oxidoreductase activity • (Methionine synthase) reductase • [methionine synthase reductase activity] Cydrannau o'r gell • cytosol • cytoplasm Prosesau biolegol • cobalamin metabolic process • cellular amino acid biosynthetic process • methionine biosynthetic process • DNA methylation • methionine metabolic process • homocysteine catabolic process • folic acid metabolic process • negative regulation of cystathionine beta-synthase activity • S-adenosylmethionine cycle • homocysteine metabolic process • sulfur amino acid metabolic process • methylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4552	n/a
Ensembl	ENSG00000124275	n/a
UniProt	Q9UBK8	n/a
RefSeq (mRNA)	NM_002454 NM_024010	n/a
RefSeq (protein)	NP_002445 NP_076915 NP_001351369 NP_001351370 NP_001351371	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MTRR yw MTRR a elwir hefyd yn Methionine synthase reductase a 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5p15.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MTRR.

• MSR
• cblE

Llyfryddiaeth

• "A66G and C524T polymorphisms of methionine synthase reductase gene are linked to the development of acyanotic congenital heart diseases in Egyptian children. ". Gene. 2017. PMID 28778621.
• "Association of Three Single Nucleotide Polymorphisms in MTR and MTRR Genes with Lung Cancer in a Turkish Population. ". Genet Test Mol Biomarkers. 2017. PMID 28537809.
• "Association between Methionine Synthase Reductase A66G Polymorphism and Male Infertility: A Meta-Analysis. ". Crit Rev Eukaryot Gene Expr. 2017. PMID 28436330.
• "Analysis of methionine synthase (rs1805087) gene polymorphism in autism patients in Northern Iran. ". Acta Neurobiol Exp (Wars). 2016. PMID 28094822.
• "Alternatively Spliced Methionine Synthase in SH-SY5Y Neuroblastoma Cells: Cobalamin and GSH Dependence and Inhibitory Effects of Neurotoxic Metals and Thimerosal.". Oxid Med Cell Longev. 2016. PMID 26989453.