MTPN

MTPN
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3AAA
Dynodwyr
Cyfenwau	MTPN, GCDP, V-1, myotrophin
Dynodwyr allanol	OMIM: 606484 HomoloGene: 40607 GeneCards: MTPN
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • sequence-specific DNA binding Cydrannau o'r gell • cytoplasm • F-actin capping protein complex • axon • perinuclear region of cytoplasm • cnewyllyn cell • cytosol Prosesau biolegol • regulation of striated muscle tissue development • catecholamine metabolic process • positive regulation of cardiac muscle hypertrophy • regulation of barbed-end actin filament capping • cellular response to mechanical stimulus • skeletal muscle tissue regeneration • neuron differentiation • striated muscle cell differentiation • regulation of translation • cerebellar granule cell differentiation • positive regulation of NF-kappaB transcription factor activity • positive regulation of cell growth • GO:0050759 positive regulation of macromolecule biosynthetic process • regulation of cell size Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	136319	n/a
Ensembl	ENSG00000105887	n/a
UniProt	P58546	n/a
RefSeq (mRNA)	NM_145808	n/a
RefSeq (protein)	NP_665807	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MTPN yw MTPN a elwir hefyd yn Myotrophin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MTPN.

• V-1
• GCDP

Llyfryddiaeth

• "cDNA sequence and characterization of the gene that encodes human myotrophin/V-1 protein, a mediator of cardiac hypertrophy. ". J Mol Cell Cardiol. 1999. PMID 10329199.
• "Cardiac myotrophin exhibits rel/NF-kappa B interacting activity in vitro. ". J Biol Chem. 1996. PMID 8576259.
• "Assignment of myotrophin to human chromosome band 7q33-->q35 by in situ hybridization. ". Cytogenet Cell Genet. 2001. PMID 11474205.
• "9-cis Retinoic acid modulates myotrophin expression and its miR in physiological and pathophysiological cell models. ". Exp Cell Res. 2017. PMID 28300567.
• "The Human Myotrophin Variant Attenuates MicroRNA-Let-7 Binding Ability but Not Risk of Left Ventricular Hypertrophy in Human Essential Hypertension.". PLoS One. 2015. PMID 26274321.