MTAP

MTAP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1SD1, 3OZD, 3OZC, 3LN5, 3OZE, 1SD2, 1CB0, 1CG6, 1K27
Dynodwyr
Cyfenwau	MTAP, BDMF, DMSFH, DMSMFH, HEL-249, LGMBF, MSAP, c86fus, methylthioadenosine phosphorylase
Dynodwyr allanol	OMIM: 156540 HomoloGene: 1838 GeneCards: MTAP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • glycosyltransferase activity • 1,4-alpha-oligoglucan phosphorylase activity • catalytic activity • GO:0001948, GO:0016582 protein binding • pentosyltransferase activity • S-methyl-5-thioadenosine phosphorylase activity Cydrannau o'r gell • extracellular exosome • cnewyllyn cell • cytosol • cytoplasm Prosesau biolegol • L-methionine salvage from methylthioadenosine • purine ribonucleoside salvage • nucleoside metabolic process • nicotinamide riboside catabolic process • nucleobase-containing compound metabolic process • interleukin-12-mediated signaling pathway • methylation • response to testosterone Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4507	n/a
Ensembl	ENSG00000099810	n/a
UniProt	Q13126	n/a
RefSeq (mRNA)	NM_002451	n/a
RefSeq (protein)	NP_002442	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MTAP yw MTAP a elwir hefyd yn Methylthioadenosine phosphorylase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 9, band 9p21.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MTAP.

• BDMF
• MSAP
• DMSFH
• LGMBF
• DMSMFH
• c86fus
• HEL-249

Llyfryddiaeth

• "Characterization of the Methylthioadenosine Phosphorylase Polymorphism rs7023954 - Incidence and Effects on Enzymatic Function in Malignant Melanoma. ". PLoS One. 2016. PMID 27479139.
• "The essential role of methylthioadenosine phosphorylase in prostate cancer. ". Oncotarget. 2016. PMID 26910893.
• "Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines. ". PLoS One. 2016. PMID 26751376.
• "Characterization and Prognostic Significance of Methylthioadenosine Phosphorylase Deficiency in Nasopharyngeal Carcinoma. ". Medicine (Baltimore). 2015. PMID 26656376.
• "Expression of Methylthioadenosine Phosphorylase (MTAP) in Pilocytic Astrocytomas.". Pathobiology. 2015. PMID 26088413.