MTA1

MTA1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4BKX, 4PBY, 4PBZ, 4PC0, 5ICN, 5FXY
Dynodwyr
Cyfenwau	MTA1, metastasis associated 1
Dynodwyr allanol	OMIM: 603526 HomoloGene: 3442 GeneCards: MTA1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • sequence-specific DNA binding • GO:0001106 transcription corepressor activity • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001105 transcription coactivator activity • zinc ion binding • chromatin binding • metal ion binding • core promoter sequence-specific DNA binding • GO:0001948, GO:0016582 protein binding • histone deacetylase activity • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • histone deacetylase binding Cydrannau o'r gell • cytoplasm • nuclear envelope • intracellular membrane-bounded organelle • nucleoplasm • microtubule • Cytosgerbwd • cnewyllyn cell • cytosol • NuRD complex Prosesau biolegol • response to ionizing radiation • GO:0009373 regulation of transcription, DNA-templated • regulation of gene expression, epigenetic • proses rythmig • circadian regulation of gene expression • transcription, DNA-templated • positive regulation of protein autoubiquitination • double-strand break repair • entrainment of circadian clock by photoperiod • GO:0072468 signal transduction • proteasome-mediated ubiquitin-dependent protein catabolic process • locomotor rhythm • histone deacetylation • negative regulation of nucleic acid-templated transcription • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • positive regulation of nucleic acid-templated transcription • GO:1901227 negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9112	n/a
Ensembl	ENSG00000182979	n/a
UniProt	Q13330	n/a
RefSeq (mRNA)	NM_001203258 NM_004689	n/a
RefSeq (protein)	NP_001190187 NP_004680	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MTA1 yw MTA1 a elwir hefyd yn Metastasis associated 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q32.33.

Llyfryddiaeth

• "Bioinformatic exploration of MTA1-regulated gene networks in colon cancer. ". Front Med. 2016. PMID 27052252.
• "Effects of silencing MTA1 gene by RNA interference on invasion and metastasis of endometrial carcinoma. ". Eur J Gynaecol Oncol. 2016. PMID 27048111.
• "Role of metastasis-associated protein 1 in prognosis of patients with digestive tract cancers: A meta-analysis. ". PLoS One. 2017. PMID 28570554.
• "Metastasis-associated protein is a predictive biomarker for metastasis and recurrence in gastric cancer. ". Oncol Rep. 2016. PMID 27574100.
• "Metastasis-associated gene 1 expression in human medulloblastoma and its association with invasion and metastasis in medulloblastoma Daoy cell lines.". Genet Mol Res. 2016. PMID 27323185.