MT2A

MT2A
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1MHU, 2MHU
Dynodwyr
Cyfenwau	MT2A, MT2, Metallothionein 2A, MT-II, MT-2
Dynodwyr allanol	OMIM: 156360 HomoloGene: 136536 GeneCards: MT2A
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • zinc ion binding Cydrannau o'r gell • cytoplasm • perinuclear region of cytoplasm • cytosol • cnewyllyn cell Prosesau biolegol • response to metal ion • cellular response to interleukin-3 • cellular response to erythropoietin • negative regulation of growth • cellular response to zinc ion • interferon-gamma-mediated signaling pathway • cellular copper ion homeostasis • cellular zinc ion homeostasis • detoxification of copper ion • cellular response to cadmium ion • cellular response to copper ion • nitric oxide mediated signal transduction • response to bacterium Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4502	n/a
Ensembl	ENSG00000125148	n/a
UniProt	P02795	n/a
RefSeq (mRNA)	NM_005953	n/a
RefSeq (protein)	NP_005944	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MT2A yw MT2A a elwir hefyd yn Metallothionein 2A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 16, band 16q13.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MT2A.

• MT2
• MT-2
• MT-II

Llyfryddiaeth

• "Zinc binds non-cooperatively to human liver metallothionein 2a at physiological pH. ". Biochem Biophys Res Commun. 2017. PMID 28865957.
• "Metallothionein polymorphisms in a Northern Spanish population with neovascular and dry forms of age-related macular degeneration. ". Ophthalmic Genet. 2017. PMID 28635422.
• "The association of the blood lead level and serum lipid concentrations may be modified by the genetic combination of the metallothionein 2A polymorphisms rs10636 GC and rs28366003 AA. ". J Clin Lipidol. 2017. PMID 28391890.
• "Genetic polymorphisms (rs10636 and rs28366003) in metallothionein 2A increase breast cancer risk in Chinese Han population. ". Aging (Albany NY). 2017. PMID 28228606.
• "Levels of heavy metals and their binding protein metallothionein in type 2 diabetics with kidney disease.". J Biochem Mol Toxicol. 2017. PMID 28059470.