MST1

MST1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2ASU, 4QT8
Dynodwyr
Cyfenwau	MST1, D3F15S2, DNF15S2, HGFL, MSP, NF15S2, macrophage stimulating 1
Dynodwyr allanol	OMIM: 142408 HomoloGene: 7360 GeneCards: MST1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • receptor tyrosine kinase binding • GO:0001948, GO:0016582 protein binding • serine-type endopeptidase activity Cydrannau o'r gell • extracellular region • extracellular space • collagen-containing extracellular matrix Prosesau biolegol • proteolysis • regulation of cAMP-dependent protein kinase activity • hepatocyte growth factor receptor signaling pathway • negative regulation of gluconeogenesis • regulation of macrophage chemotaxis • positive regulation of mammary gland epithelial cell proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4485	n/a
Ensembl	ENSG00000173531	n/a
UniProt	P26927	n/a
RefSeq (mRNA)	NM_020998 NM_001393581 NM_001393582 NM_001393583 NM_001393584 NM_001393585	n/a
RefSeq (protein)	NP_066278	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MST1 yw MST1 a elwir hefyd yn Macrophage stimulating 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3p21.31.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MST1.

• MSP
• HGFL
• NF15S2
• D3F15S2
• DNF15S2

Llyfryddiaeth

• "MST1: a promising therapeutic target to restore functional beta cell mass in diabetes. ". Diabetologia. 2016. PMID 27053234.
• "Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas. ". Respir Res. 2014. PMID 25551685.
• "The effects of macrophage-stimulating protein on the migration, proliferation, and collagen synthesis of skin fibroblasts in vitro and in vivo. ". Tissue Eng Part A. 2015. PMID 25315688.
• "Mammalian sterile-like 1 kinase inhibits TGFβ and EGF‑dependent regulation of invasiveness, migration and proliferation of HEC-1-A endometrial cancer cells. ". Int J Oncol. 2014. PMID 24841766.
• "Mst1 overexpression inhibited the growth of human non-small cell lung cancer in vitro and in vivo.". Cancer Gene Ther. 2013. PMID 23928732.