MPP5

PALS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Y76, 3UIT, 4UU5, 4UU6, 4WSI
Dynodwyr
Cyfenwau	PALS1, membrane palmitoylated protein 5, protein associated with LIN7 1, MAGUK p55 family member, MPP5, protein associated with LIN7 1, MAGUK family member
Dynodwyr allanol	OMIM: 606958 HomoloGene: 9512 GeneCards: PALS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein domain specific binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • bilen • bicellular tight junction • myelin sheath adaxonal region • Schmidt-Lanterman incisure • cell junction • lateral loop • extracellular exosome • endomembrane system • Cellbilen • GO:0009327 protein-containing complex Prosesau biolegol • establishment of epithelial cell polarity • peripheral nervous system myelin maintenance • protein localization to myelin sheath abaxonal region • myelin assembly • bicellular tight junction assembly • plasma membrane organization • morphogenesis of an epithelial sheet • protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	64398	n/a
Ensembl	ENSG00000072415	n/a
UniProt	Q8N3R9	n/a
RefSeq (mRNA)	NM_001256550 NM_022474	n/a
RefSeq (protein)	NP_001243479 NP_071919	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MPP5 yw MPP5 a elwir hefyd yn Membrane palmitoylated protein 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 14, band 14q23.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MPP5.

• PALS1

Llyfryddiaeth

• "Crystallization and preliminary X-ray data collection of the L27(PATJ)-(L27N,L27C)(Pals1)-L27(MALS) tripartite complex. ". Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID 22102253.
• "The SARS coronavirus E protein interacts with PALS1 and alters tight junction formation and epithelial morphogenesis. ". Mol Biol Cell. 2010. PMID 20861307.
• "PALS1 is essential for retinal pigment epithelium structure and neural retina stratification. ". J Neurosci. 2011. PMID 22114289.
• "Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove. ". Acta Crystallogr D Biol Crystallogr. 2015. PMID 25760605.
• "Next-generation sequencing reveals novel rare fusion events with functional implication in prostate cancer.". Oncogene. 2015. PMID 24488012.