MPP1

MPP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EJY, 2EV8, 3NEY
Dynodwyr
Cyfenwau	MPP1, AAG12, DXS552E, EMP55, MRG1, PEMP, membrane palmitoylated protein 1, MAGUK p55 scaffold protein 1
Dynodwyr allanol	OMIM: 305360 HomoloGene: 1826 GeneCards: MPP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • guanylate kinase activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cortical cytoskeleton • cell projection • integral component of plasma membrane • intracellular anatomical structure • bilen • stereocilium • cytosol • Cellbilen • nuclear speck Prosesau biolegol • regulation of neutrophil chemotaxis • GO:0072468 signal transduction • GDP metabolic process • GMP metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4354	n/a
Ensembl	ENSG00000130830	n/a
UniProt	Q00013	n/a
RefSeq (mRNA)	NM_001166460 NM_001166461 NM_001166462 NM_002436	n/a
RefSeq (protein)	NP_001159932 NP_001159933 NP_001159934 NP_002427	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MPP1 yw MPP1 a elwir hefyd yn Membrane palmitoylated protein 1 a 55 kDa erythrocyte membrane protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xq28.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MPP1.

• MRG1
• PEMP
• AAG12
• EMP55
• DXS552E

Llyfryddiaeth

• "MPP1 directly interacts with flotillins in erythrocyte membrane - Possible mechanism of raft domain formation. ". Biochim Biophys Acta. 2017. PMID 28865798.
• "MPP1 interacts with DOPC/SM/Cholesterol in an artificial membrane system using Langmuir-Blodgett monolayer. ". Gen Physiol Biophys. 2017. PMID 28653654.
• "Membrane rafts in the erythrocyte membrane: a novel role of MPP1p55. ". Adv Exp Med Biol. 2015. PMID 25408337.
• "The role of MPP1/p55 and its palmitoylation in resting state raft organization in HEL cells. ". Biochim Biophys Acta. 2013. PMID 23507198.
• "Palmitoylation of MPP1 (membrane-palmitoylated protein 1)/p55 is crucial for lateral membrane organization in erythroid cells.". J Biol Chem. 2012. PMID 22496366.