MPDZ

MPDZ
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2FCF, 2FNE, 2IWN, 2IWO, 2IWP, 2IWQ, 2O2T, 2OPG, 2QG1
Dynodwyr
Cyfenwau	MPDZ, HYC2, MUPP1, multiple PDZ domain crumbs cell polarity complex component
Dynodwyr allanol	OMIM: 603785 HomoloGene: 2841 GeneCards: MPDZ
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein C-terminus binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • neuron projection • cell junction • apicolateral plasma membrane • dendrite • postsynaptic membrane • Cellbilen • cell projection • synapse • apical plasma membrane • Schmidt-Lanterman incisure • GO:0016023 cytoplasmic vesicle • GO:0097483, GO:0097481 postsynaptic density • bilen • bicellular tight junction Prosesau biolegol • cell adhesion • GO:0022415 viral process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8777	n/a
Ensembl	ENSG00000107186	n/a
UniProt	O75970	n/a
RefSeq (mRNA)	NM_001261406 NM_001261407 NM_003829 NM_001330637	n/a
RefSeq (protein)	NP_001248335 NP_001248336 NP_001317566 NP_003820 NP_001362342 NP_001362345 NP_001362346 NP_001362347 NP_001362348 NP_001362349 NP_001362350 NP_001362351 NP_001362352 NP_001362353 NP_001362354 NP_001362355 NP_001362356 NP_001365707	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MPDZ yw MPDZ a elwir hefyd yn Multiple PDZ domain protein a Multiple PDZ domain crumbs cell polarity complex component (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9p23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MPDZ.

• HYC2
• MUPP1

Llyfryddiaeth

• "Genetic variability in the NMDA-dependent AMPA trafficking cascade is associated with alcohol dependence. ". Addict Biol. 2012. PMID 21762291.
• "Structure-based identification of CaMKIIα-interacting MUPP1 PDZ domains and rational design of peptide ligands to target such interaction in human fertilization. ". Amino Acids. 2016. PMID 26984442.
• "Evaluating the Association between Keratoconus and Reported Genetic Loci in a Han Chinese Population. ". Ophthalmic Genet. 2015. PMID 25675348.
• "The multi-PDZ domain protein-1 (MUPP-1) expression regulates cellular levels of the PALS-1/PATJ polarity complex. ". Exp Cell Res. 2013. PMID 23880463.
• "Mutation in MPDZ causes severe congenital hydrocephalus.". J Med Genet. 2013. PMID 23240096.