MNDA

MNDA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DBG
Dynodwyr
Cyfenwau	MNDA, PYHIN3, myeloid cell nuclear differentiation antigen
Dynodwyr allanol	OMIM: 159553 HomoloGene: 74438 GeneCards: MNDA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • GO:0001948, GO:0016582 protein binding • double-stranded DNA binding Cydrannau o'r gell • cytoplasm • extracellular exosome • cnewyllyn cell • extracellular region • nucleoplasm • nucleolus • azurophil granule lumen • ficolin-1-rich granule lumen Prosesau biolegol • B cell receptor signaling pathway • cellular defense response • GO:0009373 regulation of transcription, DNA-templated • negative regulation of B cell proliferation • transcription, DNA-templated • cellular response to DNA damage stimulus • positive regulation of apoptotic process • neutrophil degranulation • activation of innate immune response • cellular response to interferon-beta • positive regulation of interleukin-1 beta production Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4332	n/a
Ensembl	ENSG00000163563	n/a
UniProt	P41218	n/a
RefSeq (mRNA)	NM_002432	n/a
RefSeq (protein)	NP_002423	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MNDA yw MNDA a elwir hefyd yn Myeloid cell nuclear differentiation antigen (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MNDA.

• PYHIN3

Llyfryddiaeth

• "Value of Quantitative assessment of Myeloid Nuclear Differentiation Antigen expression and other flow cytometric parameters in the diagnosis of Myelodysplastic syndrome. ". Int J Lab Hematol. 2016. PMID 26822549.
• "Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma. ". Hum Pathol. 2014. PMID 24925224.
• "Purification, characterization and docking studies of the HIN domain of human myeloid nuclear differentiation antigen (MNDA). ". Biotechnol Lett. 2014. PMID 24557068.
• "Significance of myeloid antigen expression in precursor T lymphoblastic lymphoma. ". Chin J Cancer. 2010. PMID 20193116.
• "Identification of MNDA as a new marker for nodal marginal zone lymphoma.". Leukemia. 2009. PMID 19474799.