MIP

MIP
Dynodwyr
Cyfenwau	MIP, AQP0, CTRCT15, LIM1, MIP26, MP26, major intrinsic protein of lens fiber
Dynodwyr allanol	OMIM: 154050 HomoloGene: 40627 GeneCards: MIP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calmodulin binding • structural constituent of eye lens • water channel activity • channel activity Cydrannau o'r gell • integral component of membrane • bilen • Cellbilen • cell junction • apical plasma membrane • Reticwlwm endoplasmig • gap junction • integral component of plasma membrane Prosesau biolegol • response to stimulus • water transport • cludo transmembrane rhwng ïonau • lens development in camera-type eye • protein homotetramerization • golwg • positive regulation of cell adhesion • gap junction-mediated intercellular transport • transmembrane transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4284	n/a
Ensembl	ENSG00000135517	n/a
UniProt	P30301	n/a
RefSeq (mRNA)	NM_012064	n/a
RefSeq (protein)	NP_036196	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MIP yw MIP a elwir hefyd yn Major intrinsic protein of lens fiber (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MIP.

• AQP0
• LIM1
• MP26
• MIP26
• CTRCT15

Llyfryddiaeth

• "A novel MIP mutation in familial congenital nuclear cataracts. ". Eur J Med Genet. 2016. PMID 27456987.
• "A decrease in the permeability of aquaporin zero as a possible cause for presbyopia. ". Med Hypotheses. 2016. PMID 26615967.
• "Identification and Functional Analysis of a Novel MIP Gene Mutation Associated with Congenital Cataract in a Chinese Family. ". PLoS One. 2015. PMID 25946197.
• "A novel nonsense mutation in the MIP gene linked to congenital posterior polar cataracts in a Chinese family. ". PLoS One. 2015. PMID 25803033.
• "A novel MIP gene mutation analysis in a Chinese family affected with congenital progressive punctate cataract.". PLoS One. 2014. PMID 25033405.