MICB

MICB
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1JE6, 2WY3
Dynodwyr
Cyfenwau	MICB, PERB11.2, MHC class I polypeptide-related sequence B
Dynodwyr allanol	OMIM: 602436 HomoloGene: 88329 GeneCards: MICB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • natural killer cell lectin-like receptor binding Cydrannau o'r gell • integral component of membrane • cell surface • Cellbilen • bilen • extracellular space • external side of plasma membrane Prosesau biolegol • immune system process • gamma-delta T cell activation • GO:0022415 viral process • response to heat • cytolysis • adaptive immune response • GO:0001306 response to oxidative stress • response to retinoic acid • T cell mediated cytotoxicity • natural killer cell mediated cytotoxicity • regulation of immune response • immune response-activating cell surface receptor signaling pathway • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • natural killer cell activation • susceptibility to natural killer cell mediated cytotoxicity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4277	n/a
Ensembl	ENSG00000231179 ENSG00000224378 ENSG00000206449 ENSG00000227772 ENSG00000238289 ENSG00000231372 ENSG00000234218 ENSG00000204516	n/a
UniProt	Q29980	n/a
RefSeq (mRNA)	NM_001289160 NM_001289161 NM_005931	n/a
RefSeq (protein)	NP_001276089 NP_001276090 NP_005922	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MICB yw MICB a elwir hefyd yn MHC class I polypeptide-related sequence B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p21.33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MICB.

• PERB11.2

Llyfryddiaeth

• "Polymorphism rs3828903 within MICB Is Associated with Susceptibility to Systemic Lupus Erythematosus in a Northern Han Chinese Population. ". J Immunol Res. 2016. PMID 27433477.
• "Further diversity of the 5' promoter region of the MHC class I-related chain B gene. ". Int J Immunogenet. 2016. PMID 26707708.
• "Identification of a novel MICB allele, MICB*030, by cloning and sequencing. ". Int J Immunogenet. 2015. PMID 25990310.
• "Soluble NKG2D ligand promotes MDSC expansion and skews macrophage to the alternatively activated phenotype. ". J Hematol Oncol. 2015. PMID 25887583.
• "Soluble MICB protein levels and platelet counts during hepatitis B virus infection and response to hepatocellular carcinoma treatment.". BMC Infect Dis. 2015. PMID 25626490.