MGAT1

MGAT1
Dynodwyr
Cyfenwau	MGAT1, GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, MGAT, GnTI, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Dynodwyr allanol	OMIM: 160995 HomoloGene: 1804 GeneCards: MGAT1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • glycosyltransferase activity • transferase activity • acetylglucosaminyltransferase activity • metal ion binding • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity • manganese ion binding Cydrannau o'r gell • integral component of membrane • extracellular vesicle • Golgi membrane • Golgi apparatus • extracellular exosome • bilen Prosesau biolegol • GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation • in utero embryonic development • UDP-N-acetylglucosamine catabolic process • carbohydrate metabolic process • protein N-linked glycosylation • protein N-linked glycosylation via asparagine Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4245	n/a
Ensembl	ENSG00000131446	n/a
UniProt	P26572	n/a
RefSeq (mRNA)	NM_001114617 NM_001114618 NM_001114619 NM_001114620 NM_002406	n/a
RefSeq (protein)	NP_001108089 NP_001108090 NP_001108091 NP_001108092 NP_002397 NP_001351306 NP_001351308 NP_001351309 NP_001351310 NP_001351311 NP_001351312 NP_001351313 NP_001351314 NP_001351315 NP_001351316 NP_001351317 NP_001351318 NP_001351319 NP_001351320 NP_001351321 NP_001351322 NP_001351323 NP_001351324	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MGAT1 yw MGAT1 a elwir hefyd yn Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase a Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q35.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MGAT1.

• GnTI
• MGAT
• GLCT1
• GLYT1
• GNT-1
• GNT-I
• GLCNAC-TI

Llyfryddiaeth

• "Genetic variants near the MGAT1 gene are associated with body weight, BMI and fatty acid metabolism among adults and children. ". Int J Obes (Lond). 2012. PMID 21304485.
• "Refolding of human beta-1-2 GlcNAc transferase (GnT1) and the role of its unpaired Cys 121. ". Biochem Biophys Res Commun. 2007. PMID 17716624.
• "Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis. ". Biochem J. 1997. PMID 9020882.
• "Organization and localization to chromosome 5 of the human UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I gene. ". Biochem Biophys Res Commun. 1991. PMID 1827260.
• "Cloning and expression of N-acetylglucosaminyltransferase I, the medial Golgi transferase that initiates complex N-linked carbohydrate formation.". Proc Natl Acad Sci U S A. 1990. PMID 1702225.