MECR

MECR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1ZSY, 2VCY
Dynodwyr
Cyfenwau	MECR, CGI-63, FASN2B, NRBF1, mitochondrial trans-2-enoyl-CoA reductase, ETR1, DYTOABG
Dynodwyr allanol	OMIM: 608205 HomoloGene: 5362 GeneCards: MECR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • trans-2-enoyl-CoA reductase (NADPH) activity Cydrannau o'r gell • cytoplasm • mitocondria • cnewyllyn cell • mitochondrial matrix Prosesau biolegol • fatty acid biosynthetic process • lipid metabolism • fatty acid metabolic process • fatty acid beta-oxidation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51102	n/a
Ensembl	ENSG00000116353	n/a
UniProt	Q9BV79	n/a
RefSeq (mRNA)	NM_001024732 NM_016011 NM_001349711 NM_001349712 NM_001349713 NM_001349714 NM_001349715 NM_001349716 NM_001349717	n/a
RefSeq (protein)	NP_001019903 NP_057095 NP_001336640 NP_001336641 NP_001336642 NP_001336643 NP_001336644 NP_001336645 NP_001336646	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MECR yw MECR a elwir hefyd yn Mitochondrial trans-2-enoyl-CoA reductase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p35.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MECR.

• ETR1
• NRBF1
• CGI-63
• FASN2B
• DYTOABG

Llyfryddiaeth

• "Structural enzymological studies of 2-enoyl thioester reductase of the human mitochondrial FAS II pathway: new insights into its substrate recognition properties. ". J Mol Biol. 2008. PMID 18479707.
• "Characterization of 2-enoyl thioester reductase from mammals. An ortholog of YBR026p/MRF1'p of the yeast mitochondrial fatty acid synthesis type II. ". J Biol Chem. 2003. PMID 12654921.
• "The mitochondrial fatty acid synthesis (mtFASII) pathway is capable of mediating nuclear-mitochondrial cross talk through the PPAR system of transcriptional activation. ". Biochem Biophys Res Commun. 2013. PMID 24161390.
• "The Well-Known Gene HHIP and Novel Gene MECR Are Implicated in Small Airway Obstruction. ". Am J Respir Crit Care Med. 2016. PMID 27845578.
• "MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder.". Am J Hum Genet. 2016. PMID 27817865.