ME2

ME2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1DO8, 1EFK, 1EFL, 1GZ3, 1GZ4, 1PJ2, 1PJ3, 1PJ4, 1PJL, 1QR6
Dynodwyr
Cyfenwau	ME2, ODS1, malic enzyme 2
Dynodwyr allanol	OMIM: 154270 HomoloGene: 37615 GeneCards: ME2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • malate dehydrogenase (decarboxylating) (NAD+) activity • electron transfer activity • oxidoreductase activity • NAD binding • oxaloacetate decarboxylase activity • catalytic activity • metal ion binding • malic enzyme activity • malate dehydrogenase (decarboxylating) (NADP+) activity Cydrannau o'r gell • mitocondria • mitochondrial matrix Prosesau biolegol • regulation of NADP metabolic process • metabolaeth • pyruvate metabolic process • malate metabolic process • electron transport chain • cylch Krebs Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4200	n/a
Ensembl	ENSG00000082212	n/a
UniProt	P23368	n/a
RefSeq (mRNA)	NM_001168335 NM_002396	n/a
RefSeq (protein)	NP_001161807 NP_002387	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ME2 yw ME2 a elwir hefyd yn Malic enzyme 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18q21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ME2.

• ODS1

Llyfryddiaeth

• "Human mitochondrial NAD(P)(+)-dependent malic enzyme participates in cutaneous melanoma progression and invasion. ". J Invest Dermatol. 2015. PMID 25202825.
• "Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2. ". PLoS One. 2010. PMID 20824065.
• "Variation in the malic enzyme 2 gene: implications for the pharmacogenomics of psychotic disorders. ". Pharmacogenomics. 2007. PMID 17638511.
• "Association analysis of malic enzyme 2 gene polymorphisms with idiopathic generalized epilepsy. ". Epilepsia. 2005. PMID 16190936.
• "Functional roles of ATP-binding residues in the catalytic site of human mitochondrial NAD(P)+-dependent malic enzyme.". Biochemistry. 2005. PMID 16171388.