MDH2

MDH2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DFD, 4WLE, 4WLO, 4WLV, 4WLN, 4WLU, 4WLF
Dynodwyr
Cyfenwau	MDH2, M-MDH, MDH, MGC:3559, MOR1, Malate dehydrogenase 2, EIEE51, DEE51
Dynodwyr allanol	OMIM: 154100 HomoloGene: 55938 GeneCards: MDH2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0050229 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor • malate dehydrogenase activity • protein self-association • catalytic activity • L-malate dehydrogenase activity • oxidoreductase activity • malate dehydrogenase (NADP+) activity • RNA binding Cydrannau o'r gell • bilen • myelin sheath • mitochondrial matrix • mitocondria • mitochondrial inner membrane • extracellular exosome • cnewyllyn cell • cytoplasm Prosesau biolegol • gluconeogenesis • malate metabolic process • carboxylic acid metabolic process • internal protein amino acid acetylation • cylch Krebs • oxaloacetate metabolic process • NADH metabolic process • aerobic respiration • carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4191	n/a
Ensembl	ENSG00000146701	n/a
UniProt	P40926	n/a
RefSeq (mRNA)	NM_001282403 NM_001282404 NM_005918	n/a
RefSeq (protein)	NP_001269332 NP_001269333 NP_005909	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MDH2 yw MDH2 a elwir hefyd yn Malate dehydrogenase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q11.23.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MDH2.

• MDH
• MOR1
• M-MDH
• EIEE51
• MGC:3559

Llyfryddiaeth

• "Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene. ". J Natl Cancer Inst. 2015. PMID 25766404.
• "Tom20-mediated mitochondrial protein import in muscle cells during differentiation. ". Am J Physiol Cell Physiol. 2000. PMID 11029287.
• "Aggregation states of mitochondrial malate dehydrogenase. ". Protein Sci. 1998. PMID 9792106.
• "Enzyme levels of the NADH shuttle systems: measurements in isolated muscle fibres from humans of differing physical activity. ". Acta Physiol Scand. 1987. PMID 3591372.
• "Assignment of the genes for human beta-glucuronidase and mitochondrial malate dehydrogenase to the region pter leads to q22 of chromosome 7.". Cytogenet Cell Genet. 1977. PMID r 606506 r.