MBNL2

MBNL2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2E5S, 2RPP
Dynodwyr
Cyfenwau	MBNL2, MBLL, MBLL39, PRO2032, muscleblind like splicing regulator 2
Dynodwyr allanol	OMIM: 607327 HomoloGene: 76766 GeneCards: MBNL2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • RNA binding Cydrannau o'r gell • cytoplasm • cnewyllyn cell • nucleoplasm Prosesau biolegol • regulation of RNA splicing • mRNA processing • regulation of alternative mRNA splicing, via spliceosome • RNA splicing Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10150	n/a
Ensembl	ENSG00000139793	n/a
UniProt	Q5VZF2	n/a
RefSeq (mRNA)	NM_001306070 NM_144778 NM_207304	n/a
RefSeq (protein)	NP_001292999 NP_659002 NP_997187 NP_001369578 NP_001369579 NP_001369580 NP_001369581 NP_001369582 NP_001369583 NP_001369585 NP_001369589 NP_001369590 NP_001369592 NP_001369595 NP_001369596 NP_001369597 NP_001369598 NP_001369599 NP_001369600 NP_001369601 NP_001369602 NP_001369603 NP_001369604 NP_001369605 NP_001369606 NP_001369607 NP_001369608 NP_001369609 NP_001369610 NP_001369611 NP_001369612 NP_001369613 NP_001369614 NP_001369615 NP_001369616 NP_001369617 NP_001369618 NP_001369619 NP_001369620 NP_001369621 NP_001369622 NP_001369623 NP_001369624 NP_001369625 NP_001369626	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MBNL2 yw MBNL2 a elwir hefyd yn Muscleblind like splicing regulator 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 13, band 13q32.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MBNL2.

• MBLL
• MBLL39
• PRO2032

Llyfryddiaeth

• "Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle. ". Am J Pathol. 2009. PMID 19095965.
• "RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1. ". Nat Cell Biol. 2005. PMID 16273094.
• "Solution structure of the RNA binding domain in the human muscleblind-like protein 2. ". Protein Sci. 2009. PMID 19177353.
• "Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2. ". Biochim Biophys Acta. 2014. PMID 24440524.
• "Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy.". Neuron. 2012. PMID 22884328.