MBL2

MBL2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1HUP
Dynodwyr
Cyfenwau	MBL2, COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD, mannose binding lectin 2
Dynodwyr allanol	OMIM: 154545 HomoloGene: 110436 GeneCards: MBL2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • calcium-dependent protein binding • GO:0001948, GO:0016582 protein binding • mannose binding • signaling receptor binding • carbohydrate binding • serine-type endopeptidase activity Cydrannau o'r gell • collagen • extracellular region • cell surface • extracellular space • GO:0005578 extracellular matrix • collagen-containing extracellular matrix Prosesau biolegol • complement activation, lectin pathway • positive regulation of phagocytosis • killing by host of symbiont cells • negative regulation of viral process • immune system process • complement activation • GO:0001306 response to oxidative stress • acute-phase response • defense response to bacterium • complement activation, classical pathway • opsonization • GO:0051637 defense response to Gram-positive bacterium • innate immune response • proteolysis • growth plate cartilage chondrocyte morphogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4153	n/a
Ensembl	ENSG00000165471	n/a
UniProt	P11226	n/a
RefSeq (mRNA)	NM_000242 NM_001378373 NM_001378374	n/a
RefSeq (protein)	NP_000233 NP_001365302 NP_001365303	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MBL2 yw MBL2 a elwir hefyd yn Mannose binding lectin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q21.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MBL2.

• MBL
• MBP
• MBP1
• MBPD
• MBL2D
• MBP-C
• COLEC1
• HSMBPC

Llyfryddiaeth

• "The association of mannose-binding lectin 2 polymorphisms with outcome in very low birth weight infants. ". PLoS One. 2017. PMID 28558032.
• "HBV Viral Load and Liver Enzyme Levels May Be Associated with the Wild MBL2AA Genotype. ". Mediators Inflamm. 2017. PMID 28408790.
• "High rate of in-stent restenosis after coronary intervention in carriers of the mutant mannose-binding lectin allele. ". BMC Cardiovasc Disord. 2017. PMID 28056798.
• "Mannose-binding lectin 2 (Mbl2) gene polymorphisms are related to protein plasma levels, but not to heart disease and infection by Chlamydia. ". Braz J Med Biol Res. 2016. PMID 27982280.
• "Mannose-Binding Lectin Deficiency in Brazilian Patients with Spondyloarthritis.". Immunol Invest. 2017. PMID 27911110.