MATK

MATK
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1JWO, 1X6G, 3US4
Dynodwyr
Cyfenwau	MATK, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk, Megakaryocyte-associated tyrosine kinase
Dynodwyr allanol	OMIM: 600038 HomoloGene: 48104 GeneCards: MATK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • non-membrane spanning protein tyrosine kinase activity • kinase activity • GO:0001948, GO:0016582 protein binding • protein tyrosine kinase activity • signaling receptor binding • ATP binding Cydrannau o'r gell • cytoplasm • cytosol • bilen • extrinsic component of cytoplasmic side of plasma membrane Prosesau biolegol • cell differentiation • phosphorylation • transmembrane receptor protein tyrosine kinase signaling pathway • protein phosphorylation • positive regulation of cell population proliferation • peptidyl-tyrosine autophosphorylation • mesoderm development • cell population proliferation • innate immune response • ERBB2 signaling pathway • peptidyl-tyrosine phosphorylation • regulation of cell population proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4145	n/a
Ensembl	ENSG00000007264	n/a
UniProt	P42679	n/a
RefSeq (mRNA)	NM_002378 NM_139354 NM_139355	n/a
RefSeq (protein)	NP_002369 NP_647611 NP_647612	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MATK yw MATK a elwir hefyd yn Megakaryocyte-associated tyrosine-protein kinase a Megakaryocyte-associated tyrosine kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.3.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MATK.

• CHK
• CTK
• HYL
• Lsk
• HYLTK
• HHYLTK

Llyfryddiaeth

• "Progesterone increases csk homologous kinase in HMC-1560 human mast cells and reduces cell proliferation. ". J Cell Biochem. 2007. PMID 17492661.
• "Involvement of the N-terminal unique domain of Chk tyrosine kinase in Chk-induced tyrosine phosphorylation in the nucleus. ". Exp Cell Res. 2006. PMID 16707123.
• "Csk homologous kinase (CHK), unlike Csk, enhances MAPK activation via Ras-mediated signaling in a Src-independent manner. ". Cell Signal. 2006. PMID 16168623.
• "Multi-lobulation of the nucleus in prolonged S phase by nuclear expression of Chk tyrosine kinase. ". Exp Cell Res. 2005. PMID 15748901.
• "Differential expression of Csk homologous kinase (CHK) in normal brain and brain tumors.". Cancer. 2004. PMID 15329911.