MAPRE1

MAPRE1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1PA7, 1TXQ, 1UEG, 1VKA, 1WU9, 1YIB, 1YIG, 2HKQ, 2HL3, 2HL5, 2QJZ, 2R8U, 3GJO, 3MTU, 3TQ7, 4XA1, 4XA3, 4XA6
Dynodwyr
Cyfenwau	MAPRE1, EB1, microtubule associated protein RP/EB family member 1
Dynodwyr allanol	OMIM: 603108 HomoloGene: 56129 GeneCards: MAPRE1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • microtubule binding • protein C-terminus binding • microtubule plus-end binding • identical protein binding • RNA binding • cadherin binding • protein kinase binding Cydrannau o'r gell • microtubule plus-end • microtubule cytoskeleton • microtubule organizing center • cortical microtubule cytoskeleton • cell projection membrane • Golgi apparatus • centrosome • Cytosgerbwd • cell projection • spindle • cytoplasmic microtubule • cytosol • microtubule • cytoplasm • focal adhesion • spindle midzone • mitotic spindle astral microtubule end Prosesau biolegol • G2/M transition of mitotic cell cycle • positive regulation of microtubule plus-end binding • cell population proliferation • negative regulation of microtubule polymerization • Cellraniad • cell cycle • protein localization to microtubule • sister chromatid cohesion • negative regulation of microtubule binding • positive regulation of cell migration • ciliary basal body-plasma membrane docking • regulation of microtubule cytoskeleton organization • regulation of G2/M transition of mitotic cell cycle • GO:0034613 protein localization • cell migration • regulation of microtubule polymerization or depolymerization • positive regulation of microtubule polymerization • spindle assembly • protein localization to microtubule plus-end Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	22919	n/a
Ensembl	ENSG00000101367	n/a
UniProt	Q15691	n/a
RefSeq (mRNA)	NM_012325	n/a
RefSeq (protein)	NP_036457	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAPRE1 yw MAPRE1 a elwir hefyd yn Microtubule associated protein RP/EB family member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q11.21.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAPRE1.

• EB1

Llyfryddiaeth

• "EB1 interacts with outwardly curved and straight regions of the microtubule lattice. ". Nat Cell Biol. 2016. PMID 27617931.
• "End Binding 1 (EB1) overexpression in oral lesions and cancer: A biomarker of tumor progression and poor prognosis. ". Clin Chim Acta. 2016. PMID 27208742.
• "Characterization of a novel EB1 acetylation site important for the regulation of microtubule dynamics and cargo recruitment. ". J Cell Physiol. 2018. PMID 28777446.
• "EB1 contributes to proper front-to-back polarity in neutrophil-like HL-60 cells. ". Eur J Cell Biol. 2017. PMID 28132723.
• "Role of End Binding Protein-1 in endothelial permeability response to barrier-disruptive and barrier-enhancing agonists.". Cell Signal. 2017. PMID 27667566.