MAPKAPK3

MAPKAPK3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3FHR, 3FXW, 3R1N, 3SHE
Dynodwyr
Cyfenwau	MAPKAPK3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3, mitogen-activated protein kinase-activated protein kinase 3, MDPT3, MAPK activated protein kinase 3, MK3
Dynodwyr allanol	OMIM: 602130 HomoloGene: 55836 GeneCards: MAPKAPK3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • calcium-dependent protein serine/threonine kinase activity • calmodulin binding • kinase activity • GO:0001948, GO:0016582 protein binding • calmodulin-dependent protein kinase activity • ATP binding • MAP kinase kinase activity • protein serine/threonine kinase activity • mitogen-activated protein kinase binding Cydrannau o'r gell • cytoplasm • cytosol • nucleoplasm • cnewyllyn cell Prosesau biolegol • response to cytokine • phosphorylation • protein phosphorylation • cell surface receptor signaling pathway • response to lipopolysaccharide • vascular endothelial growth factor receptor signaling pathway • macropinocytosis • GO:0035404 peptidyl-serine phosphorylation • protein autophosphorylation • GO:0072468 signal transduction • toll-like receptor signaling pathway • MAPK cascade • GO:0007243 intracellular signal transduction Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7867	n/a
Ensembl	ENSG00000114738	n/a
UniProt	Q16644	n/a
RefSeq (mRNA)	NM_001243925 NM_001243926 NM_004635	n/a
RefSeq (protein)	NP_001230854 NP_001230855 NP_004626	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MAPKAPK3 yw MAPKAPK3 a elwir hefyd yn Mitogen-activated protein kinase-activated protein kinase 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3p21.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MAPKAPK3.

• 3PK
• MK-3
• MDPT3
• MAPKAP3
• MAPKAP-K3
• MAPKAPK-3

Llyfryddiaeth

• "Mitogen-activated 3p kinase is active in the nucleus. ". Exp Cell Res. 2004. PMID 15302577.
• "Gene activity changes in ischemically preconditioned rabbit heart gene: discovery array study. ". Heart Dis. 2002. PMID 11975836.
• "Martinique Crinkled Retinal Pigment Epitheliopathy: Clinical Stages and Pathophysiologic Insights. ". Ophthalmology. 2016. PMID 27474146.
• "High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand. ". Protein Sci. 2010. PMID 19937655.
• "A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.". Gastroenterology. 2009. PMID 19208361.